Based on 87382 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $101
Based on 11371 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. FlixBus ticket prices on this trip start at $107
Where are the popular stops in Columbus and Knoxville?
Stops in Columbus
A - Columbus Bus Station
25 E Rich St, Columbus, OH 43205, USA
Stops in Knoxville
A - 100 Kirkwood St
Knoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA100 Kirkwood St
Frequently asked questions about travelling from Columbus, OH to Knoxville, TN by bus
What is the travel distance from Columbus to Knoxville?
It's about 453 km (281 miles) from Columbus to Knoxville.
What are the departure and arrival locations for buses traveling from Columbus to Knoxville?
Buses traveling this route start their trip at Columbus Bus Station, in Columbus, and end it at 100 Kirkwood St, in Knoxville.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-17
$148
11-18
No data
Today
$140
11-20
$110
11-21
$155
11-22
No data
11-23
No data
11-24
No data
The cheapest trip from Columbus, OH to Knoxville, TN was searched and found on Nov 20, 2025 with a price of $110
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Columbus, OH to Knoxville, TN, as early as possible.
You can expect to pay from $110 to $160 for a bus ticket from Columbus, OH to Knoxville, TN based on the last 2 days. You can expect to find the cheapest price for the trip at $110 which is on 2025-11-20.