Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Chicago 95Th & Dan Ryan | Paducah Bus Station | CheapestFastest | ||||
| Bus | Downtown Greyhound Station | Paducah Bus Station | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | 537-517 W. Jackson Blvd | Paducah Bus Station | No tags |
Last refresh of the prices: Today at 5:22 AM CST.
Get from Chicago to Paducah
The journey takes about 10 hours 25 minutes, and with fares starting at just $105, it presents an excellent value for a comfortable ride.
Where are the popular stops in Chicago and Paducah?
Stops in Chicago
- A630 W Harrison St, Chicago, IL 60607, USA
- C
Polk St & Canal St
500-536 W Polk St, Chicago IL 60607, USA - D
Tornado Bus S Kedzie Ave
2807 S Kedzie Ave, Chicago, IL 60623, USA - E
Cumberland CTA
5800 N Cumberland Ave, Chicago, IL 60631, USA - F
Turimex California Ave
2139 S California Ave, Chicago, IL 60608, USA
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Frequently asked questions about travelling from Chicago to Paducah by bus
What is the travel distance from Chicago to Paducah?
The distance between Chicago and Paducah is approximately 540 km (335 miles).
What are the departure and arrival locations for buses traveling from Chicago to Paducah?
Buses departing from Downtown Greyhound Station in Chicago will take you to Paducah Bus Station in Paducah.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Paducah was searched and found on Nov 22, 2025 with a price of $97To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Chicago to Paducah, as early as possible.
You can expect to pay from $97 to $132 for a bus ticket from Chicago to Paducah based on the last 2 days. You can expect to find the cheapest price for the trip at $97 which is on 2025-11-22.
