What is the travel distance from Charleston to Florence?

The distance between Charleston and Florence is approximately 162 km (100 miles).

What are the departure and arrival locations for buses traveling from Charleston to Florence?

Buses departing from Charleston Bus Station in Charleston will take you to Florence Bus Station in Florence.

Bus Charleston to Florence from $32 | Refundable Tickets

Next bus departures

Next departures for Charleston to Florence on November 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	11:15am	4565 Gaynor Ave, North Charleston	4h 20m	3:35pm	Bus station	CheapestFastest

Next departures for Charleston to Florence on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	11:15am	4565 Gaynor Ave, North Charleston	4h 20m	3:35pm	Bus station	CheapestFastest

Next departures for Charleston to Florence on November 22
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	11:15am	4565 Gaynor Ave, North Charleston	4h 20m	3:35pm	Bus station	CheapestFastest

Next departures for Charleston to Florence on November 26
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	11:15am	4565 Gaynor Ave, North Charleston	4h 20m	3:35pm	Bus station	CheapestFastest

Last refresh of the prices: Today at 8:19 AM EST.

Compare 2 ways to go from Charleston to Florence

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Florence. The journey takes about 1 hour 34 minutes, and with fares starting at just $26, it presents an excellent value for a comfortable ride.

2train per day

1h 34mAverage Duration

149 kmDistance

14kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$34 - $61	Average Duration3h 30m	CO₂ emissions 4kg CO₂e
Train	Average Price$26 - $117	Average Duration1h 34m	CO₂ emissions 14kg CO₂e

Compare bus companies

Greyhound

3.5/587,382 reviews

Staff3.6

Timeliness2.9

Cleanliness3.3

Wifi2.4

FlixBus

3.5/511,378 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

US Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Where are the popular stops in Charleston and Florence?

Stops in Charleston

A - Charleston Bus Station

Stops in Florence

A - Florence Bus Station

B - TA Travel Center - Florence

Frequently asked questions about travelling from Charleston, SC, US to Florence, SC, US by bus

What is the travel distance from Charleston to Florence?
The distance between Charleston and Florence is approximately 162 km (100 miles).
What are the departure and arrival locations for buses traveling from Charleston to Florence?
Buses departing from Charleston Bus Station in Charleston will take you to Florence Bus Station in Florence.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-17

$48

11-18

$42

Today

$47

11-20

$45

11-21

$47

11-22

$49

11-23

$39

11-24

$37

The cheapest trip from Charleston, SC, US to Florence, SC, US was searched and found on Nov 24, 2025 with a price of $37

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Florence, SC, US, as early as possible.

You can expect to pay from $37 to $49 for a bus ticket from Charleston, SC, US to Florence, SC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $37 which is on 2025-11-24.