Bus Tickets from Charleston, SC, US to Durham, NC, US

Next bus departures

Next departures for Charleston to Durham on November 14
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Greyhound Lines, Inc. + FlixBus
Bus
4565 Gaynor Ave, North Charleston
Durham Greyhound Bus StationCheapestFastest

Last refresh of the prices: Yesterday at 12:09 PM EST.

Compare 2 ways to go from Charleston to Durham

We recommend taking the train

Among the sustainable travel choices, the train stands out as a good way to reach Durham. The journey takes about 8 hours 46 minutes, and with fares starting at just $109, it presents an excellent value for a comfortable ride.

1train per day
8h 46mAverage Duration
362 kmDistance
33kgCO₂ emissions
Bus
Average Price$55 - $169Average Duration11h 10m
9kg CO₂e
Train
Average Price$109 - $225Average Duration8h 46m
33kg CO₂e

Frequently asked questions about travelling from Charleston, SC, US to Durham, NC, US by bus

  1. What is the travel distance from Charleston to Durham?

    The distance between Charleston and Durham is approximately 370 km (230 miles).

  2. What are the departure and arrival locations for buses traveling from Charleston to Durham?

    Buses departing from Charleston Bus Station in Charleston will take you to Durham Greyhound Bus Station in Durham.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11-10
No data
11-11
$117
Today
$120
11-13
$67
11-14
No data
11-15
No data
11-16
No data
11-17
No data
busbud logoThe cheapest trip from Charleston, SC, US to Durham, NC, US was searched and found on Nov 13, 2025 with a price of $67

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Charleston, SC, US to Durham, NC, US, as early as possible.

You can expect to pay from $67 to $120 for a bus ticket from Charleston, SC, US to Durham, NC, US based on the last 2 days. You can expect to find the cheapest price for the trip at $67 which is on 2025-11-13.

What's the cheapest way to go from Charleston, SC, US to Durham, NC, US?

busbud logoThe bus is the cheapest travel choice for this destination

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