Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Baltimore Downtown Bus Station | Winston Salem Greyhound Bus Station | Cheapest | ||||
 | Bus | O'Donnell St. & Travel Plaza, Infront of TA Gas station | Winston-Salem, 1425 Silas Creek Pkwy | Fastest | ||||
| Bus | O'Donnell St. & Travel Plaza, Infront of TA Gas station | Winston-Salem, 1425 Silas Creek Pkwy | No tags | ||||
FlixBus + Greyhound Lines, Inc. | Bus | Baltimore Downtown Bus Station | Winston Salem Greyhound Bus Station | No tags | ||||
| Bus | Baltimore Downtown Bus Station | Winston Salem Greyhound Bus Station | No tags |
Last refresh of the prices: Yesterday at 9:28 PM EST.
Get from Baltimore to Winston-Salem
The journey takes about 9 hours 50 minutes, and with fares starting at just $89, it presents an excellent value for a comfortable ride.
Where are the popular stops in Baltimore and Winston-Salem?
Stops in Baltimore
- A
Baltimore Downtown Bus Station
2110 Haines St, Baltimore, MD 21230, United States - B7 St Paul St, Baltimore, MD 21201, USA
- D1578 Maryland Ave, Baltimore, MD 21201, USA
Stops in Winston-Salem
- A
Winston Salem Greyhound Bus Station
100 W 5th St, Winston Salem, NC 27101 - B
E Sprague St
841 E Sprague St, Winston-Salem, NC 27107, USA - C
Winston-Salem Bus Stop
2500 Old Lexington Rd, Winston-Salem, NC 27107, USA - D
1237 Silas Creek Pkwy
1237 Silas Creek Pkwy., Winston-Salem, NC 27127 (Hong Kong King Buffet)
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Frequently asked questions about travelling from Baltimore to Winston-Salem by bus
What is the distance between Baltimore and Winston-Salem?
Baltimore and Winston-Salem are 478 km (297 miles) apart.
What are the departure and arrival locations for buses traveling from Baltimore to Winston-Salem?
Buses departing from Baltimore Downtown Bus Station in Baltimore will take you to Winston Salem Greyhound Bus Station in Winston-Salem.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Baltimore to Winston-Salem was searched and found on Nov 28, 2025 with a price of $126To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Baltimore to Winston-Salem, as early as possible.
You can expect to pay from $126 to $277 for a bus ticket from Baltimore to Winston-Salem based on the last 2 days. You can expect to find the cheapest price for the trip at $126 which is on 2025-11-28.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
Top travelled bus routes
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Popular bus departures from Baltimore
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