Next departures for Orlando to Buffalo on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Orlando Health / Amtrak Station
Depew Station
Cheapest
Train
Orlando Health / Amtrak Station
Depew Station
Fastest
Train
Orlando Health / Amtrak Station
Depew Station
No tags
Train
Orlando Health / Amtrak Station
Exchange Street Station
No tags
Next departures for Orlando to Buffalo on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Orlando Health / Amtrak Station
Depew Station
CheapestFastest
Train
Orlando Health / Amtrak Station
Depew Station
No tags
Next departures for Orlando to Buffalo on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Train
Orlando Health / Amtrak Station
Depew Station
CheapestFastest
Train
Orlando Health / Amtrak Station
Depew Station
No tags
Train
Orlando Health / Amtrak Station
Depew Station
No tags
Train
Orlando Health / Amtrak Station
Exchange Street Station
No tags
Train
Orlando Health / Amtrak Station
Exchange Street Station
No tags
Last refresh of the prices: Yesterday at 7:04 PM EST.
Compare 2 ways to go from Orlando to Buffalo
We recommend taking the bus
Among the sustainable travel choices, the bus stands out as the good way to reach Buffalo. The journey takes about 1 day, 11 hours 15 minutes and with fares starting at just $126, it presents an excellent value for a comfortable ride.
Based on 5597 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $220
Frequently asked questions about traveling from Orlando to Buffalo, NY by train
How much does a train ticket from Orlando to Buffalo cost?
The average train ticket price from Orlando to Buffalo is $312. The best way to find train tickets from Orlando to Buffalo is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Orlando to Buffalo?
A train trip between Orlando and Buffalo is around 1d 8h, although the fastest train will take about 1d 7h. This is the time it takes to travel the 1000 miles that separates the two cities.
How many daily trains are there between Orlando and Buffalo?
The number of trains from Orlando to Buffalo can differ depending on the day of the week. On average, there are 2. Some trains are direct while others have layovers. Simplify your train trip from Orlando to Buffalo by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Orlando to Buffalo?
When taking the train from Orlando to Buffalo, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11/19
$378
11/20
$483
Today
$391
11/22
$550
11/23
$563
11/24
No data
11/25
No data
11/26
No data
The cheapest trip from Orlando to Buffalo, NY was searched and found on Nov 19, 2025 with a price of $378
To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Orlando to Buffalo, NY, as early as possible.
You can expect to pay from $378 to $2,471 for a train ticket from Orlando to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $550 which is on 2025-11-22.
The cheapest trip from Orlando to Buffalo, NY was searched and found on Nov 19, 2025 with a price of $378
