Trains tickets from Florence, SC, US to Syracuse, US

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TodayJun 29
from $285
TomorrowJun 30
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Upcoming Train Schedules

One passenger / one way

  • This trip is recommended because it is: Cheapest + Fastest
    Departure time: June 29 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: June 30 at
    Destination city: Syracuse
    Destination location: Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: June 29 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: June 30 at
    Destination city: Syracuse
    Destination location: Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: June 29 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: June 30 at
    Destination city: Syracuse
    Destination location: Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:
  • Departure time: June 29 at
    Departure city: Florence
    Departure location: Florence Station
    Arrival time: June 30 at
    Destination city: Syracuse
    Destination location: Amtrak Station
    Operated by: AmtrakAmtrak
    Vehicle: TrainDuration:

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Compare 2 ways to go from Florence to Syracuse.

Bus
Average Price$131 - $217Average Duration21h 30m
26kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Train
Average Price$275 - $445Average Duration19h 29m
94kg CO₂e1 out of 5 stars
Fastest
busbud logoBusbud recommends taking the bus from Florence to Syracuse

Among the sustainable travel choices, the bus stands out as the good way to reach Syracuse. The journey takes about 21 hours 30 minutes and with fares starting at just $131, it presents an excellent value for a comfortable ride.

2bus per day
21h 30mAverage Duration
$131Cheapest ticket
26kgCO₂ emissions

Train Florence to Syracuse: Trip Overview

Please note, this information is subject to change.

Average ticket price$316
Average train trip duration19h 29m
Number of daily trains2
Earliest train departure11:32pm
Distance642 miles (1035 km)

Florence to Syracuse Train

Busbud shows you the best train ticket fares and train schedules so you can easily plan and book a trip by train from Florence to Syracuse.

Train service from Florence to Syracuse will be provided by the most trusted companies.

Discover how much the train trip from Florence to Syracuse will cost you. Use our filters and sorting features to find the cheapest train tickets or high-end trains.

Frequently asked questions for your trip Florence, SC, US - Syracuse, US

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
06/27
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06/28
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Today
$274
06/30
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07/01
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07/02
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07/03
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07/04
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busbud logoThe cheapest trip from Florence to Syracuse was searched and found on Jun 29, 2025 with a price of $274

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence to Syracuse, as early as possible.

About Train Travel

Train Travel Tips

Do you like to go fast? With high-speed trains going faster than 300 km/h on certain routes, the time will fly by. Taking a train between Florence and Syracuse is also a great way to travel to arrive in the city centre and save more time for your stay in Syracuse.

No matter if you plan to take a regional or high-speed train to Syracuse, the planet will thank you. You’ll help to protect the beautiful landscapes that will unfold before your very eyes.

With up to 30x less CO2 emissions for your train journey between Florence and Syracuse, the train is an ecological alternative to flights or personal cars.

Make a music playlist for your train ride from Florence to Syracuse, and enjoy the scenery to tunes from your own personal soundtrack.

Did you know?

You can find dogs as passengers on the trains of Moscow, where there is a large number of stray dogs. Over time, the dogs have learned the inner workings of the rail system and it is not uncommon to find one traveling between the city and the suburbs.

Railway companies played a major role as early as 1883 in the use of time zones as we know them today.

The magnetic levitation train (Maglev for short) is currently the fastest train in the world. With a speed of 603 km/ h, it is closely followed by the French high-speed train (574.8 km / h) which remains in 2020, the fastest train to date

Will you be returning to Florence by train?

Train from Syracuse to Florence

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