Train tickets from Florence, SC, US to Pittsburgh

Next train departures

Next departures for Florence to Pittsburgh on November 24
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
AmtrakTrain
Florence Station
Union StationCheapest
AmtrakTrain
Florence Station
Union StationFastest
AmtrakTrain
Florence Station
Union StationNo tags
AmtrakTrain
Florence Station
Union StationNo tags

Last refresh of the prices: Yesterday at 4:45 AM EST.

Compare 2 ways to go from Florence to Pittsburgh

We recommend taking the bus

Among the sustainable travel choices, the bus stands out as the good way to reach Pittsburgh. The journey takes about 17 hours 45 minutes and with fares starting at just $86, it presents an excellent value for a comfortable ride.

1bus per day
17h 45mAverage Duration
432 milesDistance
17kgCO₂ emissions
Average Price$86 - $379Average Duration17h 45m
17kg CO₂e
Average Price$199 - $402Average Duration1d
63kg CO₂e

Frequently asked questions about traveling from Florence, SC, US to Pittsburgh by train

Find cheapest prices for trains

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
11/22
$370
11/23
No data
Today
$370
11/25
$282
11/26
No data
11/27
No data
11/28
No data
11/29
No data
busbud logoThe cheapest trip from Florence, SC, US to Pittsburgh was searched and found on Nov 25, 2025 with a price of $282

To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Florence, SC, US to Pittsburgh, as early as possible.

You can expect to pay from $282 to $1,345 for a train ticket from Florence, SC, US to Pittsburgh based on the last 2 days. You can expect to find the cheapest price for the trip at $282 which is on 2025-11-25.

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