Compare 2 ways to go from Buffalo to San Diego.
Busbud recommends taking the train from Buffalo to San DiegoAmong the sustainable travel choices, the train stands out as the good way to reach San Diego. The journey takes about 2 days, 15 hours 14 minutes and with fares starting at just $297, it presents an excellent value for a comfortable ride.
Train Buffalo, NY to San Diego, CA, US: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5343 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $297
Buffalo to San Diego Train
Busbud helps you find a train from Buffalo to San Diego. Get the best fare and schedule, book a round trip ticket or find trains with WiFi and electrical outlets.
We make it our job to connect you with the most dependable companies that offer train service from Buffalo to San Diego.
From train tickets to high-end trains trip from Buffalo to San Diego, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions for your trip Buffalo, NY - San Diego, CA, US
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to San Diego, CA, US was searched and found on Jul 28, 2025 with a price of $2,155To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to San Diego, CA, US, as early as possible.
You can expect to pay from $2,155 to $2,499 for a train ticket from Buffalo, NY to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at $2,155 which is on 2025-07-28.
About Train Travel
Train Travel Tips
There are many train stations in the world, check it station pages on Busbud to get all information you need.
Whether you take a regional or high-speed train to San Diego, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Buffalo and San Diego compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Make a music playlist for your train ride from Buffalo to San Diego, and enjoy the scenery to tunes from your own personal soundtrack.
Did you know?
The longest train journey in the world is between Europe and Asia. This long journey starts from Porto in Portugal and crosses the whole European continent to reach Hanoi in Vietnam in 12 days while traveling more than 17,000 km.
Railway companies played a major role as early as 1883 in the use of time zones as we know them today.
You can find the straightest railway in the world in Australia. This railway line is 478 kilometres long and is also considered the longest and straightest railway line in the world.
Top Traveled Train Routes
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