Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Roanoke Station | Greyhound Amtrak Station | CheapestFastest |
Last refresh of the prices: Yesterday at 10:01 PM EST.
Compare 2 ways to go from Roanoke to Indianapolis
Among the sustainable travel choices, the bus stands out as the good way to reach Indianapolis. The journey takes about 19 hours 35 minutes and with fares starting at just $119, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5641 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $177
Frequently asked questions about traveling from Roanoke to Indianapolis by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Roanoke to Indianapolis?
The cheapest train tickets from Roanoke to Indianapolis start from $177. The average price for this train route is around $177. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Roanoke to Indianapolis?
The average train ride duration from Roanoke to Indianapolis is 20h 37m, covering a distance of 377 miles (608 km). The quickest train can get you there in 20h 37m and is operated by Amtrak.
Which train operators service the Roanoke to Indianapolis route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Roanoke to Indianapolis?
The earliest train departs from Roanoke to Indianapolis at 6:15am. And the latest train departs at 8:38am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Roanoke to Indianapolis was searched and found on Dec 14, 2025 with a price of $455To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Roanoke to Indianapolis, as early as possible.
You can expect to pay from $455 to $510 for a train ticket from Roanoke to Indianapolis based on the last 2 days. You can expect to find the cheapest price for the trip at $455 which is on 2025-12-14.
