Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Jacksonville Amtrak Station | Depew Station | No tags | ||||
| Train | Jacksonville Amtrak Station | Depew Station | No tags | ||||
| Train | Jacksonville Amtrak Station | Exchange Street Station | No tags | ||||
| Train | Jacksonville Amtrak Station | Depew Station | No tags | ||||
| Train | Jacksonville Amtrak Station | Depew Station | No tags |
Compare 2 ways to go from Jacksonville to Buffalo
Among the sustainable travel choices, the train stands out as the good way to reach Buffalo. The journey takes about 1 day, 4 hours 31 minutes and with fares starting at just $217, it presents an excellent value for a comfortable ride.
Where are the popular train stations and stops in Jacksonville, FL and Buffalo, NY?
Train Companies
Based on 5655 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $217
Frequently asked questions about traveling from Jacksonville, FL to Buffalo, NY by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Jacksonville to Buffalo?
The cheapest train tickets from Jacksonville to Buffalo start from $217. The average price for this train route is around $328. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Jacksonville to Buffalo?
The average train ride duration from Jacksonville to Buffalo is 1d 4h, covering a distance of 881 miles (1420 km). The quickest train can get you there in 1d 4h and is operated by Amtrak.
Which train operators service the Jacksonville to Buffalo route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the train from Jacksonville to Buffalo?
The earliest train departs from Jacksonville to Buffalo at 5:11pm. And the latest train departs at 5:11pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Jacksonville, FL to Buffalo, NY was searched and found on Dec 17, 2025 with a price of $325To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Jacksonville, FL to Buffalo, NY, as early as possible.
You can expect to pay from $325 to $2,247 for a train ticket from Jacksonville, FL to Buffalo, NY based on the last 2 days. You can expect to find the cheapest price for the trip at $476 which is on 2025-12-20.
Top Traveled Train Routes
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