Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Durham Station | La Crosse, WI | No tags |
Get from Durham to La Crosse
The journey takes about 2 days, 1 hour 58 minutes and with fares starting at just $280, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5727 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $280
Frequently asked questions about traveling from Durham, NC, US to La Crosse, WI by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Durham to La Crosse?
The cheapest train tickets from Durham to La Crosse start from $280. The average price for this train route is around $285. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Durham to La Crosse?
The average train ride duration from Durham to La Crosse is 2d 1h, covering a distance of 846 miles (1364 km). The quickest train can get you there in 2d 1h and is operated by Amtrak.
Which train operators service the Durham to La Crosse route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Durham to La Crosse?
The earliest train departs from Durham to La Crosse at 7:06pm. And the latest train departs at 7:06pm.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to La Crosse, WI was searched and found on Jan 14, 2026 with a price of $269To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham, NC, US to La Crosse, WI, as early as possible.
You can expect to pay from $269 to $1,115 for a train ticket from Durham, NC, US to La Crosse, WI based on the last 2 days. You can expect to find the cheapest price for the trip at $269 which is on 2026-01-14.
