Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Chicago (Union Station), IL | Jefferson City, MO | CheapestFastest | |||||
| Chicago (Union Station), IL | Jefferson City, MO | No tags | |||||
| Chicago (Union Station), IL | Jefferson City, MO | No tags | |||||
| Chicago (Union Station), IL | Jefferson City, MO | No tags | |||||
| Chicago (Union Station), IL | Jefferson City, MO | No tags |
Last refresh of the prices: Yesterday at 4:48 AM CST.
Compare 2 ways to go from Chicago to Jefferson City
Among the sustainable travel choices, the train stands out as the good way to reach Jefferson City. The journey takes about 7 hours 46 minutes and with fares starting at just $49, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5639 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $49
Amtrak Chicago Jefferson City recent customer reviews
I didn’t like how chippy the conductors and monitors were
Aaron A.
Frequently asked questions about traveling from Chicago to Jefferson City, MO by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Chicago to Jefferson City?
The cheapest train tickets from Chicago to Jefferson City start from $49. The average price for this train route is around $65. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Chicago to Jefferson City?
The average train ride duration from Chicago to Jefferson City is 7h 46m, covering a distance of 330 miles (532 km). The quickest train can get you there in 7h 46m and is operated by Amtrak.
Which train operators service the Chicago to Jefferson City route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the train from Chicago to Jefferson City?
The earliest train departs from Chicago to Jefferson City at 7:15am. And the latest train departs at 9:50am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Chicago to Jefferson City, MO was searched and found on Dec 11, 2025 with a price of $46To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Chicago to Jefferson City, MO, as early as possible.
You can expect to pay from $46 to $351 for a train ticket from Chicago to Jefferson City, MO based on the last 2 days. You can expect to find the cheapest price for the trip at $46 which is on 2025-12-13.
What's the cheapest way to go from Chicago to Jefferson City, MO?
The train is the cheapest travel choice for this destinationThe best way to travel between Chicago and Jefferson City, MO is by train. By choosing the train, you'll get to save some money as you travel to your destination, as ticket prices cost $65 on average. If you're on a budget, you'll find cheap tickets from $49. If you're looking for the fastest way to get to Jefferson City, MO, choose the train, as it will take you from Chicago to Jefferson City, MO in about 7h 46m - that's the fastest way to get there!
