Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Exchange Street Station | Spartanburg Station | No tags | ||||
| Train | Depew Station | Spartanburg Station | No tags | ||||
| Train | Exchange Street Station | Spartanburg Station | No tags | ||||
| Train | Depew Station | Spartanburg Station | No tags | ||||
| Train | Exchange Street Station | Spartanburg Station | No tags |
Compare 2 ways to go from Buffalo to Spartanburg
Among the sustainable travel choices, the bus stands out as the good way to reach Spartanburg. The journey takes about 1 day, 2 hours 15 minutes and with fares starting at just $168, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5665 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $448
Frequently asked questions about traveling from Buffalo, NY to Spartanburg by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Buffalo to Spartanburg?
The cheapest train tickets from Buffalo to Spartanburg start from $448. The average price for this train route is around $448. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Buffalo to Spartanburg?
The average train ride duration from Buffalo to Spartanburg is 23h 36m, covering a distance of 575 miles (927 km). The quickest train can get you there in 23h 36m and is operated by Amtrak.
Which train operators service the Buffalo to Spartanburg route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the train from Buffalo to Spartanburg?
The earliest train departs from Buffalo to Spartanburg at 4:28am. And the latest train departs at 4:45am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Spartanburg was searched and found on Dec 25, 2025 with a price of $254To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Spartanburg, as early as possible.
You can expect to pay from $254 to $885 for a train ticket from Buffalo, NY to Spartanburg based on the last 2 days. You can expect to find the cheapest price for the trip at $254 which is on 2025-12-25.
