Next train departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Train | Depew Station | Union Terminal | CheapestFastest |
Last refresh of the prices: Last Tuesday at 9:32 AM EST.
Compare 2 ways to go from Buffalo to Cincinnati
Among the sustainable travel choices, the bus stands out as the good way to reach Cincinnati. The journey takes about 10 hours 55 minutes and with fares starting at just $58, it presents an excellent value for a comfortable ride.
Train Companies
Based on 5637 reviews, the company was rated 4.1 stars on Busbud. Travelers were especially satisfied with the seats and the ticket access but often complained with the wifi. Amtrak ticket prices on this trip start at $158
Frequently asked questions about traveling from Buffalo, NY to Cincinnati by train
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the train ticket from Buffalo to Cincinnati?
The cheapest train tickets from Buffalo to Cincinnati start from $158. The average price for this train route is around $178. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the train journey from Buffalo to Cincinnati?
The average train ride duration from Buffalo to Cincinnati is 1d 2h, covering a distance of 400 miles (645 km). The quickest train can get you there in 1d 2h and is operated by Amtrak.
Which train operators service the Buffalo to Cincinnati route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the train from Buffalo to Cincinnati?
The earliest train departs from Buffalo to Cincinnati at 12:39am. And the latest train departs at 12:39am.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Buffalo, NY to Cincinnati was searched and found on Dec 11, 2025 with a price of $134To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Buffalo, NY to Cincinnati, as early as possible.
You can expect to pay from $134 to $1,693 for a train ticket from Buffalo, NY to Cincinnati based on the last 2 days. You can expect to find the cheapest price for the trip at $1,226 which is on 2025-12-13.
