How much does a bus ticket from Santa Cruz de la Sierra to Uyuni cost?

The bus ticket price from Santa Cruz de la Sierra to Uyuni starts at R 647. The best way to find cheap bus tickets from Santa Cruz de la Sierra to Uyuni is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!

How long is the bus ride from Santa Cruz de la Sierra to Uyuni?

The average travel time between Santa Cruz de la Sierra and Uyuni is around 1d 10h, although the fastest bus will take about 18h. This is the time it takes to travel the 486 km that separates the two cities.

How many daily bus connections are there between Santa Cruz de la Sierra and Uyuni?

The number of buses from Santa Cruz de la Sierra to Uyuni can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Cruz de la Sierra to Uyuni by comparing and selecting the bus that fits your travel style and budget on Busbud.

Which bus companies travel from Santa Cruz de la Sierra to Uyuni?

When taking the bus from Santa Cruz de la Sierra to Uyuni, you can travel comfortably and safely with Trans Omar, 6 de Octubre, Trans Copacabana MEM 1.

Bus Santa Cruz de la Sierra to Uyuni from R 707 | Refundable Tickets

Next bus departures

Next departures from Santa Cruz de la Sierra to Uyuni on 10 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
Sin Fronteras + Exp. 11 de Julio	Bus	20:00	Estacion Bimodal	1d 8h	04:30	Uyuni	CheapestFastest

Next departures from Santa Cruz de la Sierra to Uyuni on 11 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	Cheapest
Sin Fronteras + Exp. 11 de Julio	Bus	20:00	Estacion Bimodal	1d 8h	04:30	Uyuni	Fastest
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
6 de Octubre + Exp. 11 de Julio	Bus	16:30	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
Trans Copacabana 1 MEM + Exp. 11 de Julio	Bus	18:30	Estacion Bimodal	1d 10h	04:30	Uyuni	No tags

Next departures from Santa Cruz de la Sierra to Uyuni on 12 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	Cheapest
Sin Fronteras + Exp. 11 de Julio	Bus	20:00	Estacion Bimodal	1d 8h	04:30	Uyuni	Fastest
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
6 de Octubre + Exp. 11 de Julio	Bus	16:30	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
Trans Copacabana 1 MEM + Exp. 11 de Julio	Bus	18:30	Estacion Bimodal	1d 10h	04:30	Uyuni	No tags

Next departures from Santa Cruz de la Sierra to Uyuni on 13 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	Cheapest
Sin Fronteras + Exp. 11 de Julio	Bus	20:00	Estacion Bimodal	1d 8h	04:30	Uyuni	Fastest
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
6 de Octubre + Exp. 11 de Julio	Bus	16:30	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
Trans Copacabana S.A. + Cruz del Norte	Bus	19:30	Estacion Bimodal	1d 10h	05:30	Uyuni	No tags

Next departures from Santa Cruz de la Sierra to Uyuni on 14 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	Cheapest
Sin Fronteras + Exp. 11 de Julio	Bus	20:00	Estacion Bimodal	1d 8h	04:30	Uyuni	Fastest
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
6 de Octubre + Exp. 11 de Julio	Bus	16:30	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
Trans Copacabana 1 MEM + Exp. 11 de Julio	Bus	18:30	Estacion Bimodal	1d 10h	04:30	Uyuni	No tags

Next departures from Santa Cruz de la Sierra to Uyuni on 15 November
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	Cheapest
Sin Fronteras + Exp. 11 de Julio	Bus	20:00	Estacion Bimodal	1d 8h	04:30	Uyuni	Fastest
Flota Capital + Exp. 11 de Julio	Bus	16:00	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
6 de Octubre + Exp. 11 de Julio	Bus	16:30	Estacion Bimodal	1d 12h	04:30	Uyuni	No tags
Trans Copacabana 1 MEM + Exp. 11 de Julio	Bus	18:30	Estacion Bimodal	1d 10h	04:30	Uyuni	No tags

Last refresh of the prices: Yesterday at 8:23 PM -04.

Get from Santa Cruz de la Sierra to Uyuni

This route is served by bus only

The journey takes about 1 day, 10 hours, and with fares starting at just R 647, it presents an excellent value for a comfortable ride.

2bus per day

1d 10hAverage duration

487 kmDistance

12kgCO₂ emissions

Compare bus companies

Trans Omar

3/514 reviews

Staff2.5

Timeliness1.7

Cleanliness2.8

WiFi0

Based on 14 reviews, the company was rated 2.8 stars on Busbud. Travellers were especially satisfied with the seats and the departure location but often complained with the Wi-Fi. Trans Omar ticket prices on this trip start at R 747

Trans Omar Santa Cruz de la Sierra Uyuni recent customer reviews

They informed us Less then 24 hours before the trip was we need to depart 7 hours earlier then hour we booked and if not we changing the route of the ride and also the trip will take longer. In the end, we arrived at the time we booked the ticket and they directed us to another company with very low-quality buses and the route was not as planned. We recommend not supporting this company.

אופיר כ.

7 April 2025

6 de Octubre

2.5/557 reviews

Staff3.7

Timeliness2.9

Cleanliness3.2

WiFi0

Trans Copacabana MEM 1

3/541 reviews

Staff3.3

Timeliness1.5

Cleanliness4.4

WiFi0

Flota Capital

2.5/55 reviews

Staff3.4

Timeliness1.3

Cleanliness1.3

WiFi0

BO Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Intercape, Trenitalia, Sindbad, Big Sky

Where are the popular stops in Santa Cruz de la Sierra and Uyuni?

Stops in Santa Cruz de la Sierra

A - Estacion Bimodal

Stops in Uyuni

A - Terminal de Autobuses de Uyuni

Frequently asked questions about travelling from Santa Cruz de la Sierra, BO to Uyuni by bus

How much does a bus ticket from Santa Cruz de la Sierra to Uyuni cost?
The bus ticket price from Santa Cruz de la Sierra to Uyuni starts at R 647. The best way to find cheap bus tickets from Santa Cruz de la Sierra to Uyuni is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the bus ride from Santa Cruz de la Sierra to Uyuni?
The average travel time between Santa Cruz de la Sierra and Uyuni is around 1d 10h, although the fastest bus will take about 18h. This is the time it takes to travel the 486 km that separates the two cities.
How many daily bus connections are there between Santa Cruz de la Sierra and Uyuni?
The number of buses from Santa Cruz de la Sierra to Uyuni can differ depending on the day of the week. On average, there are 2 on this route. Some buses run direct routes, while others have layovers. Simplify your bus trip from Santa Cruz de la Sierra to Uyuni by comparing and selecting the bus that fits your travel style and budget on Busbud.
Which bus companies travel from Santa Cruz de la Sierra to Uyuni?
When taking the bus from Santa Cruz de la Sierra to Uyuni, you can travel comfortably and safely with Trans Omar, 6 de Octubre, Trans Copacabana MEM 1.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

08/11

No data

09/11

R 707

Today

R 707

11/11

No data

12/11

R 707

13/11

No data

14/11

R 707

15/11

No data

The cheapest trip from Santa Cruz de la Sierra, BO to Uyuni was searched and found on 09 Nov 2025 with a price of R 707

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Cruz de la Sierra, BO to Uyuni as early as possible.

You can expect to pay from R 707 to R 707 for a bus ticket from Santa Cruz de la Sierra, BO to Uyuni based on the last 2 days. You can expect to find the cheapest price for the trip at R 707, which is on 2025-11-12.