Bus from Pisa to Palermo: Tickets & Timetables

Previously seen journeys

Next departures from Pisa to Palermo on 23 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Parcheggio Via Pietransantina
Terminal Bus PalermoNo tags
FlixBusBus
park Aurelia
Terminal Bus PalermoNo tags
FlixBusBus
Parcheggio Via Pietransantina
Terminal Bus PalermoNo tags
FlixBusBus
Parcheggio Via Pietransantina
Terminal Bus PalermoNo tags
FlixBusBus
park Aurelia
Terminal Bus PalermoNo tags

Compare 2 ways to travel from Pisa to Palermo

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 14 hours 10 minutes and with fares starting at just £61, it presents an excellent value for a comfortable ride.

1carpool per day
14h 10mAverage duration
416 milesDistance
28kgCO₂ emissions
Average price£56 - £161Average duration21h 35m
17kg CO₂e
Carpool
Average price£61 - £61Average duration14h 10m
28kg CO₂e

Frequently asked questions about travelling by bus from Pisa to Palermo

Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.

  1. How much is the bus ticket from Pisa to Palermo?

    The cheapest coach tickets from Pisa to Palermo start from £56. The average price for this route is around £104. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

  2. How long is the bus journey from Pisa to Palermo?

    The average bus journey time from Pisa to Palermo is 21h 35m, covering a distance of 416 miles. The fastest bus can take you there in 21h and is operated by FlixBus.

  3. Which bus companies service the Pisa to Palermo route?

    Several major bus companies operate on this route with 2 buses available per day.

  4. What is the earliest and latest departure time for the bus from Pisa to Palermo?

    The earliest bus departs from Pisa to Palermo at 05:45. And the latest bus departs at 17:25.

  5. What are the CO₂ emissions for the bus trip from Pisa to Palermo?

    A bus journey from Pisa to Palermo produces an estimated 17 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
21/12
£137
22/12
£136
Today
No data
24/12
£103
25/12
No data
26/12
No data
27/12
No data
28/12
No data
busbud logoThe cheapest trip from Pisa to Palermo was searched and found on 24 Dec 2025 with a price of £103

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Pisa to Palermo as early as possible.

You can expect to pay from £103 to £178 for a bus ticket from Pisa to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at £103, which is on 2025-12-24.

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