Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + Greyhound Lines Mexico | Bus | Mesa Bus Stop | San Antonio Bus Station | CheapestFastest |
Last refresh of the prices: Yesterday at 08:21 MST.
Get from Mesa to San Antonio
The journey takes about 1 day, 3 hours 15 minutes, and with fares starting at just £139, it presents an excellent value for a comfortable ride.
Where are the popular stops in Mesa and San Antonio?
Stops in Mesa
- A
Mesa Bus Station
1423 S Country Club , Mesa, AZ 85210, USA
Stops in San Antonio
- A500 N St Mary's St, San Antonio, TX 78205, USA
- B7914 Interstate 35 Access Rd, San Antonio, TX 78224, USA
- C165 Bowie St, San Antonio, 78205
- D4407 S PanAm Expy #101, San Antonio, TX 78225, USA
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £153
Frequently asked questions about travelling by bus from Mesa to San Antonio, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Mesa to San Antonio?
The cheapest coach tickets from Mesa to San Antonio start from £139. The average price for this route is around £183. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Mesa to San Antonio?
The average bus journey time from Mesa to San Antonio is 1d 3h, covering a distance of 831 miles. The fastest bus can take you there in 19h 35m and is operated by Greyhound.
Which bus companies service the Mesa to San Antonio route?
Several major bus companies operate on this route with 2 buses available per day.
What is the earliest and latest departure time for the bus from Mesa to San Antonio?
The earliest bus departs from Mesa to San Antonio at 03:50. And the latest bus departs at 19:15.
What are the CO₂ emissions for the bus trip from Mesa to San Antonio?
A bus journey from Mesa to San Antonio produces an estimated 33 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mesa to San Antonio, US was searched and found on 12 Jan 2026 with a price of £81To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mesa to San Antonio, US as early as possible.
You can expect to pay from £81 to £143 for a bus ticket from Mesa to San Antonio, US based on the last 2 days. You can expect to find the cheapest price for the trip at £81, which is on 2026-01-12.
