Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound Lines, Inc. + FlixBus | Bus | Lake Charles (City Point) | San Diego (Old Town-FlixBus) | Cheapest | ||||
 | Bus | Lake Charles (City Point) | Greyhound Bus Stop | Fastest | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Lake Charles (City Point) | San Diego (Old Town-FlixBus) | No tags | ||||
| Bus | Lake Charles (City Point) | Greyhound Bus Stop | No tags | ||||
Greyhound Lines, Inc. + FlixBus | Bus | Lake Charles (City Point) | UCSD Health La Jolla Station | No tags |
Last refresh of the prices: Yesterday at 23:46 CST.
Compare 2 ways to travel from Lake Charles to San Diego
Among the sustainable travel choices, the train stands out as a good way to reach San Diego. The journey takes about 1 day, 21 hours 55 minutes and with fares starting at just £223, it presents an excellent value for a comfortable ride.
Where are the popular stops in Lake Charles and San Diego?
Stops in Lake Charles
- A
Lake Charles Greyhound
1825 I-10, Lake Charles, LA 70601, USA - B
Waffle House Lake Charles
804 N Lakeshore Dr, Lake Charles, LA 70601, USA
Stops in San Diego
- A
Mission Valley Sheraton
1433 Camino del Rio S, San Diego, CA 92108, USA - B
Old Town Courtyard Marriot
2435 Jefferson St, San Diego, CA 92110, USA - C
Downtown Holiday Inn
1617 1st Ave, San Diego, CA 92101, USA - D
Greyhound Station
1313 National Ave, San Diego, CA 92101, USA - E
Market St. & Park Blvd
601 Park Boulevard, San Diego, CA 92101, USA - F
San Ysidro McDonald's
727 E San Ysidro Blvd, San Diego, CA 92173, USA
Compare bus companies
Based on 87447 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £188
Frequently asked questions about travelling by bus from Lake Charles to San Diego, CA, US
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Lake Charles to San Diego?
The cheapest coach tickets from Lake Charles to San Diego start from £186. The average price for this route is around £314. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Lake Charles to San Diego?
The average bus journey time from Lake Charles to San Diego is 2d 3h, covering a distance of 1420 miles. The fastest bus can take you there in 1d 22h and is operated by Greyhound.
Which bus companies service the Lake Charles to San Diego route?
Several major bus companies operate on this route with 7 buses available per day.
What is the earliest and latest departure time for the bus from Lake Charles to San Diego?
The earliest bus departs from Lake Charles to San Diego at 08:30. And the latest bus departs at 21:10.
What are the CO₂ emissions for the bus trip from Lake Charles to San Diego?
A bus journey from Lake Charles to San Diego produces an estimated 57 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Lake Charles to San Diego, CA, US was searched and found on 24 Dec 2025 with a price of £361To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lake Charles to San Diego, CA, US as early as possible.
You can expect to pay from £361 to £381 for a bus ticket from Lake Charles to San Diego, CA, US based on the last 2 days. You can expect to find the cheapest price for the trip at £361, which is on 2025-12-24.
