Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Des Moines | Pensacola Airport | CheapestFastest |
Last refresh of the prices: Yesterday at 09:13 CST.
Get from Des Moines to Pensacola
The journey takes about 1 day, 19 hours 5 minutes, and with fares starting at just £170, it presents an excellent value for a comfortable ride.
Where are the popular stops in Des Moines and Pensacola?
Stops in Des Moines
- A
Jefferson/Trailways Depot
1501 2nd Ave North, Des Moines, IA 50314 - B
1514 East Grand Ave
1514 East Grand Avenue,, Des Moins, IA, 50316
Stops in Pensacola
- A7950 Pensacola Blvd, Pensacola, FL 32534, USA
- B505 W Burgess Rd, Pensacola, FL 32503
Compare bus companies
Based on 87518 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi‑Fi. Greyhound ticket prices on this trip start at £170
Frequently asked questions about travelling by bus from Des Moines to Pensacola
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Des Moines to Pensacola?
The cheapest coach tickets from Des Moines to Pensacola start from £170. The average price for this route is around £171. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Des Moines to Pensacola?
The average bus journey time from Des Moines to Pensacola is 1d 19h, covering a distance of 848 miles. The fastest bus can take you there in 1d 19h and is operated by Greyhound.
Which bus companies service the Des Moines to Pensacola route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Des Moines to Pensacola?
The earliest bus departs from Des Moines to Pensacola at 09:25. And the latest bus departs at 09:45.
What are the CO₂ emissions for the bus trip from Des Moines to Pensacola?
A bus journey from Des Moines to Pensacola produces an estimated 34 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Des Moines to Pensacola was searched and found on 29 Jan 2026 with a price of £168To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Des Moines to Pensacola as early as possible.
You can expect to pay from £168 to £174 for a bus ticket from Des Moines to Pensacola based on the last 2 days. You can expect to find the cheapest price for the trip at £168, which is on 2026-02-01.
