Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Cincinnati Bus Station | Knoxville Bus Station | CheapestFastest |
Last refresh of the prices: Today at 15:57 EST.
Get from Cincinnati to Knoxville
The journey takes about 5 hours 35 minutes, and with fares starting at just £34, it presents an excellent value for a comfortable ride.
Where are the popular stops in Cincinnati and Knoxville?
Stops in Cincinnati
- A1005 Gilbert Ave, Cincinnati, OH 45202
- B
Northland Blvd
290-322 Northland Blvd, Springdale, OH 45246, USA
Stops in Knoxville
- AKnoxville Area Transit Bus Stop, 100 Kirkwood St, Knoxville, TN 37914, USA
Compare bus companies
Based on 87473 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £34
Greyhound Cincinnati Knoxville recent customer reviews
30 minute delay plus air conditioner was broken on bus very uncomfortable for my very first bus ride
Jaicelyn T.
Driver was a substitute for absent driver and very apprehensive about anyone approaching or talking with a moderate decibel. Bus felt like the The front was shaking due to an unbalanced tire. When inquiring with the bus driver he said he had to leave the resistant break on from the time we left Lexington until Knoxville
Michael N.
Frequently asked questions about travelling by bus from Cincinnati to Knoxville, TN
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Cincinnati to Knoxville?
The cheapest coach tickets from Cincinnati to Knoxville start from £34. The average price for this route is around £55. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Cincinnati to Knoxville?
The average bus journey time from Cincinnati to Knoxville is 5h 35m, covering a distance of 224 miles. The fastest bus can take you there in 5h 35m and is operated by Greyhound.
Which bus companies service the Cincinnati to Knoxville route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from Cincinnati to Knoxville?
The earliest bus departs from Cincinnati to Knoxville at 13:20. And the latest bus departs at 13:20.
What are the CO₂ emissions for the bus trip from Cincinnati to Knoxville?
A bus journey from Cincinnati to Knoxville produces an estimated 9 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Cincinnati to Knoxville, TN was searched and found on 2 Jan 2026 with a price of £41To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Cincinnati to Knoxville, TN as early as possible.
You can expect to pay from £41 to £45 for a bus ticket from Cincinnati to Knoxville, TN based on the last 1 days. You can expect to find the cheapest price for the trip at £45, which is on 2026-01-03.
