Previously seen journeys
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Big Pine Key, FL | Downtown Greyhound Station | No tags | ||||
| Bus | Big Pine Key, FL | Chicago 95Th & Dan Ryan | No tags | ||||
| Bus | Big Pine Key, FL | Downtown Greyhound Station | No tags | ||||
FlixBus + Greyhound | Bus | Big Pine Key, FL | Chicago 95Th & Dan Ryan | No tags | ||||
| Bus | Big Pine Key, FL | 537-517 W. Jackson Blvd | No tags |
Get from Big Pine Key to Chicago
The journey takes about 1 day, 15 hours 20 minutes, and with fares starting at just £173, it presents an excellent value for a comfortable ride.
Compare bus companies
Based on 87492 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the Wi-Fi. Greyhound ticket prices on this trip start at £173
Frequently asked questions about travelling by bus from Big Pine Key to Chicago
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Big Pine Key to Chicago?
The cheapest coach tickets from Big Pine Key to Chicago start from £173. The average price for this route is around £179. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Big Pine Key to Chicago?
The average bus journey time from Big Pine Key to Chicago is 1d 15h, covering a distance of 1229 miles. The fastest bus can take you there in 1d 10h and is operated by Greyhound.
Which bus companies service the Big Pine Key to Chicago route?
Several major bus companies operate on this route with 5 buses available per day.
What is the earliest and latest departure time for the bus from Big Pine Key to Chicago?
The earliest bus departs from Big Pine Key to Chicago at 10:40. And the latest bus departs at 17:40.
What are the CO₂ emissions for the bus trip from Big Pine Key to Chicago?
A bus journey from Big Pine Key to Chicago produces an estimated 50 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Big Pine Key to Chicago was searched and found on 8 Jan 2026 with a price of £169To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Big Pine Key to Chicago as early as possible.
You can expect to pay from £169 to £181 for a bus ticket from Big Pine Key to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at £169, which is on 2026-01-11.
