Next departures to Karlsruhe
One passenger / one way
- This trip is recommended because it is the: CheapestDeparture time: July 16 atDeparture city: WuppertalDeparture location: WuppertalArrival time: July 17 atDestination city: KarlsruheDestination location: Südseite HauptbahnhofOperated by: Flixbus
Vehicle: BusDuration: - This trip is recommended because it is the: Fastest
Last refresh of the prices: Last Sunday at 7:49 PM CEST.
Prices and availability are subject to change.
Accepted payments
Compare 2 ways to go from Wuppertal to Karlsruhe
Busbud recommends taking the train from Wuppertal to KarlsruheAmong the sustainable travel choices, the train stands out as a good way to reach Karlsruhe. The journey takes about 3 hours 29 minutes, and with fares starting at just US$46, it presents an excellent value for a comfortable ride.
Bus Wuppertal to Karlsruhe: Trip Overview
Compare bus companies
Based on 9551 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at US$37
Wuppertal to Karlsruhe Bus
Busbud helps you find a bus from Wuppertal to Karlsruhe. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.
We make it our job to connect you with the most dependable bus companies that cover bus service from Wuppertal to Karlsruhe.
Discover how much the bus trip from Wuppertal to Karlsruhe will cost you. Use our filters and sorting features to find the cheapest bus tickets or luxury buses.
Where are the popular stops in Wuppertal and Karlsruhe?
Frequently asked questions on the trip Wuppertal - Karlsruhe
What is the distance between Wuppertal and Karlsruhe?
The distance covered from Wuppertal to Karlsruhe is 267 km (166 miles).
What are the departure and arrival locations for buses traveling from Wuppertal to Karlsruhe?
Buses traveling this route start their trip at Wuppertal, in Wuppertal, and end it at Südseite Hauptbahnhof, in Karlsruhe.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Wuppertal to Karlsruhe was searched and found on Jul 16, 2025 with a price of US$33To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Wuppertal to Karlsruhe, as early as possible.
You can expect to pay from US$33 to US$33 for a bus ticket from Wuppertal to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at US$33 which is on 2025-07-16.
About Bus Travel
Bus Travel Tips
Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Wuppertal and Karlsruhe!
From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Wuppertal to Karlsruhe.
Buses have one of the smallest carbon footprints of motorized transport modes. A bus going from Wuppertal to Karlsruhe will emit less CO2 than a car or an airplane.
Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Wuppertal to Karlsruhe.
Did you know?
Did you know there are on average 4,400 intercity bus departures every day in the US only? This number has been growing for 9 years in a row, yay!
One of the longest bus route in the world goes all the way from Ontario to Alberta in Canada (with the same bus). This trip is 3,435 km or 2,135 miles long and the price is a bit under $100.
Did you know that 80% of the buses in North America are equipped with WiFi and power outlets ? And 60% of bus travellers have used their electronic device on board during 2014.
What's the cheapest way to go from Wuppertal to Karlsruhe?
The bus is the cheapest travel choice for this destinationTop travelled bus routes
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