Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
FlixBus + Greyhound Lines, Inc. | Bus | Gateway Station | University of South Florida | Cheapest | ||||
 | Bus | Gateway Station | Tampa Bus Station | Fastest | ||||
 | Bus | Gateway Station | Tampa Bus Station | No tags |
Last refresh of the prices: Yesterday at 9:34 AM CST.
Compare 2 ways to go from St. Louis to Tampa
Among the sustainable travel choices, the bus stands out as a good way to reach Tampa. The journey takes about 1 day, 8 hours, and with fares starting at just $164, it presents an excellent value for a comfortable ride.
Where are the popular stops in St. Louis and Tampa?
Stops in Tampa
- A
Tampa 13th Avenue Bus Stop (McDonald's)
2101 E 13th Ave (McDonald's), Tampa, FL 33605 - B
Tampa USF, FL
3801 USF Holly Drive, Tampa., FL 33620, USA - C
Greyhound Station
610 E Polk St, Tampa, FL 33602, USA - D
E Sligh Ave
11555 E Sligh Ave, Seffner, FL 33584, USA - E
N Marion St & E Laurel St
551 E Laurel St, Tampa, FL 33602, USA - F
Port of Tampa
200-298 FL-60, Tampa, FL 33602, USA
Compare bus companies
Frequently asked questions about travelling from St. Louis to Tampa by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from St. Louis to Tampa?
The cheapest bus tickets from St. Louis to Tampa start from $164. The average price for this route is around $234. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from St. Louis to Tampa?
The average bus travel time from St. Louis to Tampa is 1d 8h, covering a distance of 1378 km. The quickest bus can get you there in 21h 55m and is operated by FlixBus.
Which bus companies service the St. Louis to Tampa route?
What are the earliest and latest departure times for the bus from St. Louis to Tampa?
The earliest bus departs from St. Louis to Tampa at 1:00am. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from St. Louis to Tampa?
A bus trip from St. Louis to Tampa generates an estimated 34 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from St. Louis to Tampa?
According to Busbud customers, the highest-rated bus company on this route is FlixBus, with an average rating of 3.5 out of 5 stars based on 11828 reviews.
Which bus company has the best Wi-Fi from St. Louis to Tampa?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from St. Louis to Tampa?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from St. Louis to Tampa?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is FlixBus, with a cleanliness rating of 4.1 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from St. Louis to Tampa was searched and found on Jan 8, 2026 with a price of $201To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from St. Louis to Tampa, as early as possible.
You can expect to pay from $201 to $412 for a bus ticket from St. Louis to Tampa based on the last 2 days. You can expect to find the cheapest price for the trip at $201 which is on 2026-01-08.
Usually Greyhound will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from St. Louis to Tampa?
The bus is the cheapest travel choice for this destination
