Bus Tickets from Siena to Milano

Next departures

Next departures for Siena to Milano on October 15
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
Itabus
Siena Train Station
LampugnanoCheapest
Itabus
Siena Train Station
Milan Via Giuseppe ImpastatoFastest
Itabus
Siena Train Station
LampugnanoNo tags
Itabus
Siena Train Station
LampugnanoNo tags
Itabus
Siena Train Station
LampugnanoNo tags

Last refresh of the prices: Today at 11:34 AM CEST.

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Compare 2 ways to go from Siena to Milano

Bus
Average PriceUS$14 - US$154Average Duration6h 19m
8kg CO₂e5 out of 5 stars
CheapestMost eco-friendly
Carpool
Average PriceUS$20 - US$44Average Duration3h 50m
12kg CO₂e4 out of 5 stars
Fastest
busbud logoBusbud recommends carpooling from Siena to Milano

Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 3 hours 50 minutes, and with fares starting at just US$20, it presents an excellent value for a comfortable ride.

6carpool per day
3h 50mAverage Duration
US$20Cheapest ticket
12kgCO₂ emissions

Bus Siena to Milano: Trip Overview

Average Ticket PriceUS$27
Average Bus Trip Duration6h 19m
Number of daily buses28
Earliest bus departure12:45am
Distance329 km
Latest bus departure11:55pm

Siena to Milano Bus

Busbud helps you find a bus from Siena to Milano. Get the best fare and schedule, book a round trip ticket or find buses with WiFi and electrical outlets.

We make it our job to connect you with the most dependable bus companies that cover bus service from Siena to Milano.

From cheap bus tickets to more luxurious buses travelling from Siena to Milano, we offer a wide range of bus services to best suit your needs depending on how much your budget is.

Frequently asked questions on the trip Siena - Milano

  1. What is the travel distance from Siena to Milano?

    The distance between Siena and Milano is around 294 km (182 miles).

  2. What are the departure and arrival locations for buses traveling from Siena to Milano?

    Buses traveling this route start their trip at Piazza Gramsci, in Siena, and end it at Piazza I Maggio, 1, in Milano.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
10-12
US$51
10-13
US$59
Today
US$28
10-15
US$22
10-16
US$12
10-17
US$13
10-18
US$18
10-19
US$25
busbud logoThe cheapest trip from Siena to Milano was searched and found on Oct 16, 2025 with a price of US$12

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Siena to Milano, as early as possible.

You can expect to pay from US$12 to US$87 for a bus ticket from Siena to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at US$12 which is on 2025-10-16.

Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.

About Bus Travel

Bus Travel Tips

Make friends with the driver. They usually know a lot about your destination and may even recommend which side of the bus to sit on to get the best views on the road between Siena and Milano!

From miles long of beauteous natural landscapes to impressive man-crafted sights, you’re bound to be in for a visual treat on your bus trip from Siena to Milano.

Taking the bus creates the smallest carbon footprint compared to other modes of transport. Not to mention that buses will allow you to discover scenic gems from Siena to Milano that are otherwise impossible to come by with a plane.

Create your own real life musical score by curating a personalized bus travel playlist - the perfect accompaniment to your bus ride from Siena to Milano.

Did you know?

It takes 27 hours to go by bus from Lima to Cusco, one of the craziest bus trips on the world. This route is used daily by locals and backpackers.

Did you know some bus companies in Germany offer to their passenger low-costs snacks and regional beer based on their destination? Prosit!

The Superbus, created by a Dutch engineer is the world's fastest bus with 250 km/h. Too bad it's only a prototype for now.

What's the cheapest way to go from Siena to Milano?

busbud logoThe bus is the cheapest travel choice for this destination

Will you be returning to Siena by bus?

Bus from Milano to Siena

Why choose Busbud?

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