Next departures for Palermo to Syracuse on November 18
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on November 19
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on November 20
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on November 21
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on November 23
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Next departures for Palermo to Syracuse on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Terminal Bus Palermo
Syracuse bus station
Cheapest
Bus
Palermo Oreto Orsi
Syracuse bus station
Fastest
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Bus
Terminal Bus Palermo
Terminal Interbus
No tags
Bus
Terminal Bus Palermo
Syracuse bus station
No tags
Last refresh of the prices: Yesterday at 4:53 PM CET.
Compare 3 ways to go from Palermo to Syracuse
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Syracuse. The journey takes about 3 hours 10 minutes, and with fares starting at just $20, it presents an excellent value for a comfortable ride.
The bus service receives high praise for its punctuality, cleanliness, and comfortable seating. Passengers appreciate the friendly and helpful drivers who ensure a smooth journey. The onboard amenities like Wi-Fi are valued by travelers. However, some passengers noted issues with ticketing options from certain locations and occasional disturbances from fellow travelers using mobile phones loudly during trips.
Interbus Palermo Syracuse recent customer reviews
driver was approachable and friendly. On time and felt safe. Made sure that all passengers are in before going especially when we had our toilet stop over.
5 out of 5 stars
Ellen A.
The trip was great and the driver was excellent. Only thing I dislike was a couple that has used their mobiles the whole trip in a extremly loud way for everything.
5 out of 5 stars
Susanne N.
The bus was on time and seats were fine
It advertised free WiFi but there was no automatic connection Reading the bar code just put me into the app no connection with WiFi. WHY NO SIGN just simply giving the password
I asked the driver who was disinterested and claimed he had no idea about WiFi
I tried to charge my phone with the outlet no power so my phone was flat by the time I arrived
Not a great experience
A pity Flix only operate occasionally
Maybe Interbus management should try travelling by Flix to learn how a bus company should operate. Learn from people who know !
Hopefully I can book for a more professional organisation for my return trip to Palermo
Based on 11359 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $29
Piazzale della Stazione Centrale, 21, 96100 Siracusa SR, Italy
C - Siracusa - Terminal Bus (Stazione FS)
Viale Teocrito, 68-74, 96100 Siracusa SR, Italy
Frequently asked questions about travelling from Palermo to Syracuse by bus
How far is Palermo from Syracuse?
The distance between Palermo and Syracuse is approximately 206 km (128 miles).
What are the departure and arrival locations for buses traveling from Palermo to Syracuse?
Buses departing from Terminal Bus Palermo in Palermo will take you to Fermata dell'autobus Siracusa in Syracuse.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-16
$27
11-17
$27
Today
$27
11-19
$27
11-20
$27
11-21
$27
11-22
$27
11-23
$27
The cheapest trip from Palermo to Syracuse was searched and found on Nov 22, 2025 with a price of $27
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Palermo to Syracuse, as early as possible.
You can expect to pay from $27 to $50 for a bus ticket from Palermo to Syracuse based on the last 2 days. You can expect to find the cheapest price for the trip at $27 which is on 2025-11-22.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Palermo to Syracuse?
The bus is the cheapest travel choice for this destination
The cheapest trip from Palermo to Syracuse was searched and found on Nov 22, 2025 with a price of $27
The bus is the cheapest travel choice for this destination
