Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Fermata dell'autobus Ostuni | Rome Tiburtina Bus Station | Cheapest | ||||
| Bus | Ostuni Viale dello Sport | Rome Tiburtina Bus Station | Fastest | ||||
 | Bus | Fermata dell'autobus Ostuni | Rome Tiburtina Bus Station | No tags | ||||
 | Bus | Ostuni Viale dello Sport | Rome Tiburtina Bus Station | No tags | ||||
| Bus | Fermata dell'autobus Ostuni | Rome Fiumicino Airport | No tags |
Last refresh of the prices: Last Friday at 10:16 PM CET.
Compare 3 ways to go from Ostuni to Rome
Among the sustainable travel choices, the train stands out as a good way to reach Rome. The journey takes about 5 hours 21 minutes, and with fares starting at just $143, it presents an excellent value for a comfortable ride.
Where are the popular stops in Ostuni and Rome?
Stops in Ostuni
- AOstuni (SS 379 AREA DI SERVIZIO Q8), La stazione si trova sulla SS379, al parcheggio del benzinaio Q8., 72017 Ostuni BR, Italy
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Frequently asked questions about travelling from Ostuni to Rome by bus
What is the travel distance from Ostuni to Rome?
Ostuni and Rome are 446 km (277 miles) apart.
What are the departure and arrival locations for buses traveling from Ostuni to Rome?
Buses departing from Fermata dell'autobus Ostuni in Ostuni will take you to Rome Tiburtina Bus Station in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Ostuni to Rome was searched and found on Dec 1, 2025 with a price of $16To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Ostuni to Rome, as early as possible.
You can expect to pay from $16 to $164 for a bus ticket from Ostuni to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $16 which is on 2025-12-01.
Usually Itabus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
