What is the travel distance from Milano to Palermo?

It's about 888 km (551 miles) from Milano to Palermo.

What are the departure and arrival locations for buses traveling from Milano to Palermo?

Buses traveling this route start their trip at Milan San Donato Bus Station, in Milano, and end it at Terminal Bus Palermo, in Palermo.

Bus Milano to Palermo from $87 | Refundable Tickets

Next bus departures

Next departures for Milano to Palermo on November 20
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	CheapestFastest
	Bus	9:40am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 21
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	10:00am	Lampugnano	21h 45m	7:45am	Terminal Bus Palermo	Cheapest
	Bus	10:45am	Milan San Donato Bus Station	21h	7:45am	Terminal Bus Palermo	Fastest

Next departures for Milano to Palermo on November 22
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	10:10am	Aeroporto Linate Airport (LIN)	1d 4h	2:25pm	Terminal Bus Palermo	Cheapest
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Fastest
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	9:40am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	2:45pm	Milan (San Donato M3)	23h 40m	2:25pm	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 23
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	CheapestFastest
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	10:00am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	2:45pm	Milan (San Donato M3)	23h 40m	2:25pm	Terminal Bus Palermo	No tags
Bus	7:05am	Piazza I Maggio, 1	1d 3h	11:00am	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 24
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Cheapest
Bus	10:45am	Milan San Donato Bus Station	21h	7:45am	Terminal Bus Palermo	Fastest
Bus	10:00am	Lampugnano	21h 45m	7:45am	Terminal Bus Palermo	No tags
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	9:40am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 25
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	9:05am	Milan (Assago M2)	1d 1h	11:00am	Terminal Bus Palermo	Cheapest
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Fastest
Bus	3:30pm	Lampugnano bus station	22h 55m	2:25pm	Terminal Bus Palermo	No tags
Bus	8:50am	Milan (San Donato M3)	1d 2h	11:00am	Terminal Bus Palermo	No tags
Bus	11:45am	Piazza I Maggio, 1	1d 2h	2:25pm	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 26
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Cheapest
Bus	10:45am	Milan San Donato Bus Station	21h	7:45am	Terminal Bus Palermo	Fastest
Bus	10:00am	Lampugnano	21h 45m	7:45am	Terminal Bus Palermo	No tags
Bus	8:50am	Milan (San Donato M3)	1d 2h	11:00am	Terminal Bus Palermo	No tags
Bus	9:05am	Milan (Assago M2)	1d 1h	11:00am	Terminal Bus Palermo	No tags

Next departures for Milano to Palermo on November 27
Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
Bus	7:05am	Piazza I Maggio, 1	1d 3h	11:00am	Terminal Bus Palermo	Cheapest
Bus	12:55pm	Lampugnano bus station	22h 5m	11:00am	Terminal Bus Palermo	Fastest
Bus	9:40am	Milan (San Donato M3)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	9:05am	Milan (Assago M2)	1d 1h	11:00am	Terminal Bus Palermo	No tags
Bus	5:25am	Milan (Malpensa Aeroporto Terminal 1)	1d 5h	11:00am	Terminal Bus Palermo	No tags

Last refresh of the prices: Today at 6:08 AM CET.

Compare 2 ways to go from Milano to Palermo

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Palermo. The journey takes about 16 hours 40 minutes, and with fares starting at just $114, it presents an excellent value for a comfortable ride.

1carpool per day

16h 40mAverage Duration

887 kmDistance

37kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions	Actions
Bus	Average Price$51 - $444	Average Duration1d 2h	CO₂ emissions 22kg CO₂e
Carpool	Average Price$114 - $204	Average Duration16h 40m	CO₂ emissions 37kg CO₂e

Compare bus companies

FlixBus

3.5/511,380 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

Autoservizi Salemi

4.5/5450 reviews

Staff4.9

Timeliness4.3

Cleanliness4.7

Wifi3.9

Itabus

4/5945 reviews

Staff4.3

Timeliness3

Cleanliness4.3

Wifi3.1

OneBus

4/513 reviews

Staff5

Timeliness3.9

Cleanliness4.4

Wifi5

IT Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Where are the popular stops in Milano and Palermo?

Stops in Milano

A - Milan San Donato Bus Station

B - Linate Airport

C - Piazza I Maggio, 1

D - Lampugnano

E - Malpensa Airport

F - Molino Dorino

Stops in Palermo

A - Terminal Bus Palermo

B - Palermo Airport

C - Piazza Cairoli

D - Fiera

E - Via Paolo Balsamo, 21

F - Via Paolo Balsamo, 31

Frequently asked questions about travelling from Milano to Palermo by bus

What is the travel distance from Milano to Palermo?
It's about 888 km (551 miles) from Milano to Palermo.
What are the departure and arrival locations for buses traveling from Milano to Palermo?
Buses traveling this route start their trip at Milan San Donato Bus Station, in Milano, and end it at Terminal Bus Palermo, in Palermo.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-18

$223

11-19

$296

Today

$218

11-21

$151

11-22

$129

11-23

$120

11-24

$103

11-25

$91

The cheapest trip from Milano to Palermo was searched and found on Nov 25, 2025 with a price of $91

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Palermo, as early as possible.

You can expect to pay from $91 to $296 for a bus ticket from Milano to Palermo based on the last 2 days. You can expect to find the cheapest price for the trip at $91 which is on 2025-11-25.