Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Milan Via Giuseppe Impastato | Messina Centrale | Cheapest | ||||
 | Bus | Lampugnano bus station | Messina Centrale | Fastest | ||||
 | Bus | Milan San Donato Bus Station | Piazza della Repubblica | No tags | ||||
| Bus | Lampugnano | Messina Centrale | No tags | ||||
| Bus | Lampugnano bus station | Messina Centrale | No tags |
Last refresh of the prices: Last Tuesday at 6:32 PM CET.
Compare 2 ways to go from Milano to Messina
Among the sustainable travel choices, the carpool stands out as a good way to reach Messina. The journey takes about 12 hours 30 minutes, and with fares starting at just $84, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$44 - $356 | Average Duration21h 20m | 24kg CO₂e | ||
Carpool | Average Price$84 - $180 | Average Duration12h 30m | 41kg CO₂e |
Where are the popular stops in Milano and Messina?
Stops in Milano
- APiazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
- BVia Giulio Natta, 228, 20151 Milano, Italy
- DVia Giuseppe Impastato, 27, 20138 Milano, Italy
- F
Molino Dorino
Molino Dorino, 20151 Milano, Italy
Stops in Messina
- A
Piazza della Repubblica
Via Guido delle Colonne, 49, 98122 Messina ME, Italy - BPiazza Stazione, 98122 Messina ME, Italy
- C
Via Giuseppe Garibaldi 263
Via Giuseppe Garibaldi 263, 98122 Messina ME, Italy - D
Porto
Capitaneria di Porto, Via Vittorio Emanuele II, 111, 98100 Messina ME, Italy
Compare bus companies
Frequently asked questions about travelling from Milano to Messina by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Milano to Messina?
The cheapest bus tickets from Milano to Messina start from $44. The average price for this route is around $123. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Milano to Messina?
The average bus travel time from Milano to Messina is 21h 20m, covering a distance of 971 km. The quickest bus can get you there in 17h 15m and is operated by FlixBus.
Which bus companies service the Milano to Messina route?
Several major bus companies operate on this route with 25 buses available per day, including services from FlixBus, Itabus, Autoservizi Salemi.
What are the earliest and latest departure times for the bus from Milano to Messina?
The earliest bus departs from Milano to Messina at 12:00am. And the latest bus departs at 11:50pm.
What are the CO₂ emissions for the bus trip from Milano to Messina?
A bus trip from Milano to Messina generates an estimated 24 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Milano to Messina?
According to Busbud customers, the highest-rated bus company on this route is Autoservizi Salemi, with an average rating of 4.3 out of 5 stars based on 450 reviews.
Which bus company has the best Wi-Fi from Milano to Messina?
Based on Busbud reviews, the bus company Autoservizi Salemi has the highest Wi-Fi rating with a score of 3.9.
Which bus company has the best on-time performance from Milano to Messina?
According to Busbud traveller reviews, the most punctual bus company on this route is Autoservizi Salemi, with a punctuality rating of 4.3 out of 5 stars.
Which bus company has the cleanest buses from Milano to Messina?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Autoservizi Salemi, with a cleanliness rating of 4.7 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Milano to Messina was searched and found on Nov 29, 2025 with a price of $56To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Milano to Messina, as early as possible.
You can expect to pay from $56 to $248 for a bus ticket from Milano to Messina based on the last 2 days. You can expect to find the cheapest price for the trip at $56 which is on 2025-11-29.
Usually Itabus, Autoservizi Salemi will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Milano to Messina?
The bus is the cheapest travel choice for this destination
