Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | ZOB | Lyon - Perrache Bus Station | Cheapest | ||||
| Bus | ZOB | Lyon - Perrache Bus Station | Fastest |
Last refresh of the prices: Yesterday at 7:07 PM CET.
Compare 3 ways to go from Mannheim to Lyon
Among the sustainable travel choices, the carpool stands out as a good way to reach Lyon. The journey takes about 6 hours 20 minutes, and with fares starting at just $96, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$48 - $158 | Average Duration13h 35m | 12kg CO₂e | ||
Train | Average Price$74 - $353 | Average Duration5h 18m | 12kg CO₂e | |
Carpool | Average Price$96 - $106 | Average Duration6h 20m | 21kg CO₂e |
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Where are the popular stops in Mannheim and Lyon?
Frequently asked questions about travelling from Mannheim to Lyon by bus
What is the travel distance from Mannheim to Lyon?
The distance between Mannheim and Lyon is approximately 498 km (309 miles).
What are the departure and arrival locations for buses traveling from Mannheim to Lyon?
Buses departing from ZOB in Mannheim will take you to Perrache in Lyon.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Mannheim to Lyon was searched and found on Nov 20, 2025 with a price of $45To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Mannheim to Lyon, as early as possible.
You can expect to pay from $45 to $137 for a bus ticket from Mannheim to Lyon based on the last 2 days. You can expect to find the cheapest price for the trip at $45 which is on 2025-11-20.
What's the cheapest way to go from Mannheim to Lyon?
The bus is the cheapest travel choice for this destination
