Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Manfredonia | Rome Tiburtina Bus Station | Cheapest | ||||
 | Bus | Manfredonia | Rome Tiburtina Bus Station | Fastest | ||||
| Bus | Manfredonia | Rome Fiumicino Airport | No tags | ||||
| Bus | Manfredonia | Rome Fiumicino Airport | No tags | ||||
| Bus | Manfredonia | Aeroporto Ciampino Airport (CIA) | No tags |
Last refresh of the prices: Today at 4:50 AM CET.
Compare 2 ways to go from Manfredonia to Rome
Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 4 hours 10 minutes, and with fares starting at just $37, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$42 - $95 | Average Duration6h 35m | 7kg CO₂e | ||
Carpool | Average Price$37 - $71 | Average Duration4h 10m | 12kg CO₂e |
Where are the popular stops in Manfredonia and Rome?
Stops in Rome
- ALargo Guido Mazzoni, 3, 00162 Roma, Italy
- D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy - E
Roma
- F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy
Compare bus companies
Frequently asked questions about travelling from Manfredonia to Rome by bus
What is the travel distance from Manfredonia to Rome?
The distance between Manfredonia and Rome is around 286 km (178 miles).
What are the departure and arrival locations for buses traveling from Manfredonia to Rome?
Buses traveling this route start their trip at Manfredonia, in Manfredonia, and end it at Rome Tiburtina Bus Station, in Rome.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Manfredonia to Rome was searched and found on Nov 24, 2025 with a price of $36To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Manfredonia to Rome, as early as possible.
You can expect to pay from $36 to $88 for a bus ticket from Manfredonia to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $36 which is on 2025-11-24.
Usually FlixBus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
