Next departures for Lyon to Karlsruhe on November 22
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lyon - Perrache Bus Station
Karlsruhe
CheapestFastest
Bus
Lyon - Perrache Bus Station
Karlsruhe
No tags
Next departures for Lyon to Karlsruhe on November 24
Operated by
Vehicle type
Departure time
Departure location
Trip duration
Arrival time
Arrival location
Recommended
Price and booking link
Bus
Lyon - Perrache Bus Station
Karlsruhe
CheapestFastest
Last refresh of the prices: Today at 5:34 PM CET.
Compare 3 ways to go from Lyon to Karlsruhe
We recommend carpooling
Among the sustainable travel choices, the carpool stands out as a good way to reach Karlsruhe. The journey takes about 5 hours 30 minutes, and with fares starting at just $71, it presents an excellent value for a comfortable ride.
Based on 11362 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. FlixBus ticket prices on this trip start at $49
Based on 11137 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the ticket access and the staff but often complained with the WiFi. BlaBlaCar Bus ticket prices on this trip start at $37
Frequently asked questions about travelling from Lyon to Karlsruhe by bus
What is the travel distance from Lyon to Karlsruhe?
The distance between Lyon and Karlsruhe is approximately 450 km (279 miles).
What are the departure and arrival locations for buses traveling from Lyon to Karlsruhe?
Buses departing from Perrache in Lyon will take you to Südseite Hauptbahnhof in Karlsruhe.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
Best price found
11-16
$35
11-17
$47
Today
$35
11-19
No data
11-20
$41
11-21
No data
11-22
$35
11-23
$35
The cheapest trip from Lyon to Karlsruhe was searched and found on Nov 22, 2025 with a price of $35
To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Lyon to Karlsruhe, as early as possible.
You can expect to pay from $35 to $60 for a bus ticket from Lyon to Karlsruhe based on the last 2 days. You can expect to find the cheapest price for the trip at $35 which is on 2025-11-22.
What's the cheapest way to go from Lyon to Karlsruhe?
The bus is the cheapest travel choice for this destination
The cheapest trip from Lyon to Karlsruhe was searched and found on Nov 22, 2025 with a price of $35
The bus is the cheapest travel choice for this destination
