What is the distance between Karlsruhe and Milano?

The distance covered from Karlsruhe to Milano is 399 km (248 miles).

What are the departure and arrival locations for buses traveling from Karlsruhe to Milano?

Buses traveling this route start their trip at Südseite Hauptbahnhof, in Karlsruhe, and end it at Lampugnano, in Milano.

Bus Karlsruhe to Milano from $45 | Refundable Tickets

Next departures

Next departures for Karlsruhe to Milano on November 26
Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
3:20am	Südseite Hauptbahnhof	8h 15m	11:35am	Lampugnano bus station	Cheapest
9:30am	Südseite Hauptbahnhof	7h 20m	4:50pm	Lampugnano bus station	Fastest
10:05pm	Südseite Hauptbahnhof	8h 30m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags
10:05pm	Südseite Hauptbahnhof	8h 20m	6:25am	Aeroporto Malpensa T2	No tags
8:10pm	Südseite Hauptbahnhof	8h 55m	5:05am	Lampugnano bus station	No tags

Next departures for Karlsruhe to Milano on November 27
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	3:20am	Südseite Hauptbahnhof	8h 15m	11:35am	Lampugnano bus station	Cheapest
	11:00pm	Südseite Hauptbahnhof	8h 10m	7:10am	Lampugnano bus station	Fastest
	10:05pm	Südseite Hauptbahnhof	8h 30m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags
Flixtrain + Flixbus	7:10pm	Karlsruhe Hbf	11h 25m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags
	9:05pm	Karlsruhe	23h 15m	8:20pm	Lampugnano	No tags

Next departures for Karlsruhe to Milano on November 28
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
		9:05pm	Karlsruhe	17h	2:05pm	Lampugnano	CheapestFastest
		11:15am	Karlsruhe	18h 45m	6:00am	Lampugnano	No tags

Next departures for Karlsruhe to Milano on November 29
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	9:30am	Südseite Hauptbahnhof	7h 20m	4:50pm	Lampugnano bus station	CheapestFastest
	9:30am	Südseite Hauptbahnhof	10h 35m	8:05pm	Milan (Malpensa Aeroporto Terminal 1)	No tags
Flixtrain + Flixbus	7:10pm	Karlsruhe Hbf	11h 25m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags
	9:30am	Südseite Hauptbahnhof	11h 10m	8:40pm	Milan Via Giuseppe Impastato	No tags
	10:05pm	Südseite Hauptbahnhof	8h 30m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags

Next departures for Karlsruhe to Milano on November 30
Operated by	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended
	9:30am	Südseite Hauptbahnhof	7h 20m	4:50pm	Lampugnano bus station	CheapestFastest
	9:30am	Südseite Hauptbahnhof	10h 35m	8:05pm	Milan (Malpensa Aeroporto Terminal 1)	No tags
Flixtrain + Flixbus	7:10pm	Karlsruhe Hbf	11h 25m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags
	11:15am	Karlsruhe	18h 45m	6:00am	Lampugnano	No tags
	10:05pm	Südseite Hauptbahnhof	8h 30m	6:35am	Milan (Malpensa Aeroporto Terminal 1)	No tags

Last refresh of the prices: Yesterday at 5:44 PM CET.

Compare 3 ways to go from Karlsruhe to Milano

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Milano. The journey takes about 5 hours 50 minutes, and with fares starting at just $64, it presents an excellent value for a comfortable ride.

1carpool per day

5h 50mAverage Duration

399 kmDistance

17kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$50 - $185	Average Duration8h 55m	CO₂ emissions 10kg CO₂e
Train	Average Price$300 - $300	Average Duration13h 17m	CO₂ emissions 9kg CO₂e
Carpool	Average Price$64 - $82	Average Duration5h 50m	CO₂ emissions 17kg CO₂e

Where are the popular stops in Karlsruhe and Milano?

Stops in Karlsruhe

A
Südseite Hauptbahnhof
Hinterm Hauptbahnhof 6, 76137 Karlsruhe, Germany
Visit page
B
Karlsruhe Hbf
Bahnhofpl. 1A, 76137 Karlsruhe, Germany
Visit page
C
Goethestraße
Goethestraße 17-19, 76135 Karlsruhe, Germany
Visit page
D
Karlsruhe
Gartenstraße 58, 76135 Karlsruhe, Germany
E
Karlsruhe/Baden-Baden Airport
Quebec Avenue, 77836 Rheinmünster, Germany

Stops in Milano

A
Lampugnano
Via Giulio Natta, 228, 20151 Milano, Italy
Visit page
B
Linate Airport
Visit page
C
Piazza I Maggio, 1
Piazza I Maggio, 1, 20099 Sesto San Giovanni MI, Italy
Visit page
D
Malpensa Airport
Visit page
E
Milan San Donato Bus Station
Via Giuseppe Impastato, 27, 20138 Milano, Italy
Visit page
F
Molino Dorino
Molino Dorino, 20151 Milano, Italy

Compare bus companies

FlixBus

3.5/511,446 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

BlaBlaCar Bus

3.5/511,160 reviews

Staff4.4

Timeliness3.6

Cleanliness4.3

Wifi2.6

MarinoBus

4/5896 reviews

Staff4.7

Timeliness4.3

Cleanliness4.3

Wifi3.3

IT Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about travelling from Karlsruhe to Milano by bus

What is the distance between Karlsruhe and Milano?
The distance covered from Karlsruhe to Milano is 399 km (248 miles).
What are the departure and arrival locations for buses traveling from Karlsruhe to Milano?
Buses traveling this route start their trip at Südseite Hauptbahnhof, in Karlsruhe, and end it at Lampugnano, in Milano.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-24

$57

11-25

$44

Today

$55

11-27

$45

11-28

$93

11-29

$49

11-30

$51

12-01

$47

The cheapest trip from Karlsruhe to Milano was searched and found on Nov 25, 2025 with a price of $44

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Karlsruhe to Milano, as early as possible.

You can expect to pay from $44 to $171 for a bus ticket from Karlsruhe to Milano based on the last 2 days. You can expect to find the cheapest price for the trip at $45 which is on 2025-11-27.

Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.