Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Brussels-South (Gare du Midi) | Estación Sur | Cheapest | ||||
| Bus | Brussels-South (Gare du Midi) | Aeropuerto Madrid - Barajas T4 (E) | Fastest | ||||
| Bus | Brussels-South (Gare du Midi) | Estación Sur | No tags | ||||
 | Bus | Brussels Airport | Madrid (South) | No tags | ||||
| Bus | Brussels Airport | Madrid (South) | No tags |
Last refresh of the prices: Yesterday at 5:13 PM CET.
Compare 2 ways to go from Brussels to Madrid
Among the sustainable travel choices, the carpool stands out as a good way to reach Madrid. The journey takes about 16 hours 50 minutes, and with fares starting at just $133, it presents an excellent value for a comfortable ride.
| Average Price | Average Duration | CO₂ emissions | Actions | |
|---|---|---|---|---|
| Average Price$71 - $385 | Average Duration22h 30m | 33kg CO₂e | ||
Carpool | Average Price$133 - $235 | Average Duration16h 50m | 55kg CO₂e |
Where are the popular stops in Brussels and Madrid?
Stops in Brussels
- ARue de France 85, 1060 Saint-Gilles, Belgium
- BBoulevard Simon Bolivar 7, 1030 Schaerbeek, Belgium
- CPachecolaan 5, 1000 Brussel, Belgium
- D
Centrale
Rue de Loxum 5, 1000 Bruxelles, Belgium
Stops in Madrid
- BMendez Alvaro, 83, , Madrid, 28045, Spain
- CAvenida de América, 9, 28002 Madrid, Spain
- DPlaza Moncloa, 671, 28008 Madrid, Spain
- E
Madrid Interc. Plaza Castilla
Madrid Interc. Plaza Castilla, 28046 Madrid, Spain - F
Ronda de Valencia 6
Ronda de Valencia 6, 28012 Madrid, Spain
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Frequently asked questions about travelling from Brussels to Madrid by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Brussels to Madrid?
The cheapest bus tickets from Brussels to Madrid start from $71. The average price for this route is around $141. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Brussels to Madrid?
The average bus travel time from Brussels to Madrid is 22h 30m, covering a distance of 1320 km. The quickest bus can get you there in 20h and is operated by BlaBlaCar Bus.
Which bus companies service the Brussels to Madrid route?
Several major bus companies operate on this route with 14 buses available per day, including services from FlixBus, BlaBlaCar Bus.
What are the earliest and latest departure times for the bus from Brussels to Madrid?
The earliest bus departs from Brussels to Madrid at 12:45am. And the latest bus departs at 10:55pm.
What are the CO₂ emissions for the bus trip from Brussels to Madrid?
A bus trip from Brussels to Madrid generates an estimated 33 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
What is the best bus company from Brussels to Madrid?
According to Busbud customers, the highest-rated bus company on this route is BlaBlaCar Bus, with an average rating of 3.7 out of 5 stars based on 11143 reviews.
Which bus company has the best Wi-Fi from Brussels to Madrid?
Based on Busbud reviews, the bus company FlixBus has the highest Wi-Fi rating with a score of 2.7.
Which bus company has the best on-time performance from Brussels to Madrid?
According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.
Which bus company has the cleanest buses from Brussels to Madrid?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is BlaBlaCar Bus, with a cleanliness rating of 4.3 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Brussels to Madrid was searched and found on Dec 3, 2025 with a price of $84To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Brussels to Madrid, as early as possible.
You can expect to pay from $84 to $272 for a bus ticket from Brussels to Madrid based on the last 2 days. You can expect to find the cheapest price for the trip at $84 which is on 2025-12-03.
Usually BlaBlaCar Bus will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.
What's the cheapest way to go from Brussels to Madrid?
The bus is the cheapest travel choice for this destination
