What is the travel distance from Alessandria to Rome?

Alessandria and Rome are 459 km (285 miles) apart.

What are the departure and arrival locations for buses traveling from Alessandria to Rome?

Buses departing from Alessandria in Alessandria will take you to Rome Tiburtina Bus Station in Rome.

Bus Alessandria to Rome from $61 | Refundable Tickets

Next bus departures

Next departures for Alessandria to Rome on November 24
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	7:25pm	Alessandria	9h 5m	4:30am	Rome Tiburtina Bus Station	Cheapest
	Bus	10:45pm	Alessandria	8h 15m	7:00am	Rome Tiburtina Bus Station	Fastest

Last refresh of the prices: Yesterday at 4:23 AM CET.

Compare 3 ways to go from Alessandria to Rome

We recommend carpooling

Among the sustainable travel choices, the carpool stands out as a good way to reach Rome. The journey takes about 6 hours 10 minutes, and with fares starting at just $58, it presents an excellent value for a comfortable ride.

2carpool per day

6h 10mAverage Duration

459 kmDistance

19kgCO₂ emissions

	Average Price	Average Duration	CO₂ emissions
Bus	Average Price$62 - $135	Average Duration9h 5m	CO₂ emissions 11kg CO₂e
Train	Average Price$90 - $209	Average Duration6h 2m	CO₂ emissions 11kg CO₂e
Carpool	Average Price$58 - $79	Average Duration6h 10m	CO₂ emissions 19kg CO₂e

Where are the popular stops in Alessandria and Rome?

Stops in Alessandria

A
Alessandria
Piazza Eugenio Curiel, 15121 Alessandria
Visit page
B
Fermata dell'autobus Alessandria
Strada Alessandria 42, 15122 Alessandria AL, Italy

Stops in Rome

A
Rome Tiburtina Bus Station
Largo Guido Mazzoni, 3, 00162 Roma, Italy
Visit page
B
Rome Ciampino Airport
Visit page
C
Rome Fiumicino Airport
Visit page
D
Castro Pretorio
Viale Castro Pretorio 76, 00185 Roma, Italy
E
Roma
F
Anagnina
Via Vincenzo Giudice, 00173 Roma RM, Italy

Compare bus companies

FlixBus

3.5/511,422 reviews

Staff4.2

Timeliness3.9

Cleanliness4.1

Wifi2.7

BusItalia

4/5158 reviews

Staff5

Timeliness2.8

Cleanliness4.5

Wifi3.7

MarinoBus

4/5895 reviews

Staff4.7

Timeliness4.3

Cleanliness4.3

Wifi3.3

IT Bus Companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Rede Expressos, Trenitalia

Frequently asked questions about travelling from Alessandria to Rome by bus

What is the travel distance from Alessandria to Rome?
Alessandria and Rome are 459 km (285 miles) apart.
What are the departure and arrival locations for buses traveling from Alessandria to Rome?
Buses departing from Alessandria in Alessandria will take you to Rome Tiburtina Bus Station in Rome.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11-22

$57

11-23

$71

Today

$80

11-25

$76

11-26

$66

11-27

$67

11-28

$73

11-29

$61

The cheapest trip from Alessandria to Rome was searched and found on Nov 22, 2025 with a price of $57

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Alessandria to Rome, as early as possible.

You can expect to pay from $57 to $103 for a bus ticket from Alessandria to Rome based on the last 2 days. You can expect to find the cheapest price for the trip at $61 which is on 2025-11-29.

Usually BusItalia will charge you higher prices for tickets closer to the departure date. To find the best prices, you should be flexible on your date of travel.