How much is the bus ticket from São Paulo to Sao Thome das Letras?

The cheapest bus tickets from São Paulo to Sao Thome das Letras start from $49. The average price for this route is around $50. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.

How long is the bus ride from São Paulo to Sao Thome das Letras?

The average bus trip duration from São Paulo to Sao Thome das Letras is 6h, covering a distance of 163 miles (262 km). The quickest bus can get you there in 6h and is operated by Viação Santa Cruz .

Which bus companies service the São Paulo to Sao Thome das Letras route?

Several major train operators operate on this route with 1 trains available per day.

What is the earliest and latest departure time for the bus from São Paulo to Sao Thome das Letras?

The earliest bus departs from São Paulo to Sao Thome das Letras at 10:30pm. And the latest bus departs at 11:30pm.

What are the CO₂ emissions for the bus trip from São Paulo to Sao Thome das Letras?

A bus trip from São Paulo to Sao Thome das Letras generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Bus São Paulo to Sao Thome das Letras from $42 | Refundable Tickets

Next bus departures

Next departures for São Paulo to Sao Thome das Letras on November 30
Operated by	Vehicle type	Departure time	Departure location	Trip duration	Arrival time	Arrival location	Recommended	Price and booking link
	Bus	10:30pm	Rodoviária do Tietê	6h	4:30am	Sao Tome das Letras	CheapestFastest

Last refresh of the prices: Today at 11:19 AM -03.

Get from São Paulo to Sao Thome das Letras

This route is served by bus only

The journey takes about 6 hours and with fares starting at just $49, it presents an excellent value for a comfortable ride.

1bus per day

6hAverage Duration

163 milesDistance

7kgCO₂ emissions

Compare bus companies

Viação Santa Cruz

4/570 reviews

Staff4.6

Timeliness4.3

Cleanliness4.3

Wifi3

Based on 70 reviews, the company was rated 4.2 stars on Busbud. Travelers were especially satisfied with the staff and the departure location but often complained with the wifi. Viação Santa Cruz ticket prices on this trip start at $49

BR bus companies: FlixBus, BlaBlaCar Bus, ALSA, Greyhound, Intercape, Trenitalia, Sindbad

Frequently asked questions about traveling from São Paulo to Sao Thome das Letras by bus

Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.

How much is the bus ticket from São Paulo to Sao Thome das Letras?
The cheapest bus tickets from São Paulo to Sao Thome das Letras start from $49. The average price for this route is around $50. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from São Paulo to Sao Thome das Letras?
The average bus trip duration from São Paulo to Sao Thome das Letras is 6h, covering a distance of 163 miles (262 km). The quickest bus can get you there in 6h and is operated by Viação Santa Cruz.
Which bus companies service the São Paulo to Sao Thome das Letras route?
Several major train operators operate on this route with 1 trains available per day.
What is the earliest and latest departure time for the bus from São Paulo to Sao Thome das Letras?
The earliest bus departs from São Paulo to Sao Thome das Letras at 10:30pm. And the latest bus departs at 11:30pm.
What are the CO₂ emissions for the bus trip from São Paulo to Sao Thome das Letras?
A bus trip from São Paulo to Sao Thome das Letras generates an estimated 7 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found

11/26

$42

11/27

$42

Today

No data

11/29

No data

11/30

$44

12/01

No data

12/02

No data

12/03

No data

The cheapest trip from São Paulo to Sao Thome das Letras was searched and found on Nov 26, 2025 with a price of $42

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from São Paulo to Sao Thome das Letras, as early as possible.

You can expect to pay from $42 to $44 for a bus ticket from São Paulo to Sao Thome das Letras based on the last 2 days. You can expect to find the cheapest price for the trip at $44 which is on 2025-11-30.