Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
Greyhound + FlixBus | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
Greyhound + FlixBus | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
FlixBus + Greyhound | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
 | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags |
Get from Panama City to Port Saint Lucie
The journey takes about 13 hours 25 minutes and with fares starting at just $139, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Port Saint Lucie?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Panama City, US to Port Saint Lucie by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Port Saint Lucie?
The cheapest bus tickets from Panama City to Port Saint Lucie start from $139. The average price for this route is around $151. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Port Saint Lucie?
The average bus trip duration from Panama City to Port Saint Lucie is 13h 25m, covering a distance of 382 miles (616 km). The quickest bus can get you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Panama City to Port Saint Lucie route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Panama City to Port Saint Lucie?
The earliest bus departs from Panama City to Port Saint Lucie at 7:25am. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from Panama City to Port Saint Lucie?
A bus trip from Panama City to Port Saint Lucie generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
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