Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Panama City Beach Station | Lake City Bus Station | No tags | ||||
| Bus | Panama City Beach Station | Lake City Bus Station | No tags | ||||
| Bus | Panama City Beach Station | Lake City Bus Station | No tags | ||||
| Bus | Panama City Beach Station | Lake City Bus Station | No tags | ||||
| Bus | Panama City Beach Station | Lake City Bus Station | No tags |
Get from Panama City to Lake City
The journey takes about 5 hours and with fares starting at just $41, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Lake City?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Lake City
- A2470 W US HWY 90, Lake City, FL 32025, USA
- B
Lake City Greyhound Bus Station
251 S MARION AVE , 32055, Florida
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Greyhound Lines offers the most comprehensive intercity bus services in the United States. They operate a modern, environmentally friendly fleet that serves more than 2400 destinations and carries nearly 16 million passengers annually. When traveling with them, you can expect free WiFi, onboard entertainment, bathrooms, power outlets and decent legroom. One of the great perks of Greyhound is that they connect big cities and smaller towns in the US, where you usually can't get to by train or plane. If you're looking for safe and affordable transportation, Greyhound is a great choice.
Frequently asked questions about traveling from Panama City, US to Lake City by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Lake City?
The cheapest bus tickets from Panama City to Lake City start from $41. The average price for this route is around $41. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Lake City?
The average bus trip duration from Panama City to Lake City is 5h, covering a distance of 187 miles (302 km). The quickest bus can get you there in 5h and is operated by Greyhound.
Which bus companies service the Panama City to Lake City route?
Several major train operators operate on this route with 2 trains available per day.
What is the earliest and latest departure time for the bus from Panama City to Lake City?
The earliest bus departs from Panama City to Lake City at 7:30am. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from Panama City to Lake City?
A bus trip from Panama City to Lake City generates an estimated 8 kg of CO₂, making it a highly eco-friendly travel option and recommended mode of travel by Busbud.
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Popular bus departures from Panama City
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