Next departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Durham Station | Chicago (Union Station), IL | CheapestFastest | |||||
| Durham Station | Chicago (Union Station), IL | No tags | |||||
| Durham Station | Chicago (Union Station), IL | No tags |
Last refresh of the prices: Today at 12:50 PM EST.
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Compare 2 ways to travel from Durham to Chicago
Among the sustainable travel choices, the bus stands out as a good way to reach Chicago. The journey takes about 1 day, 2 hours 5 minutes and with fares starting at just US$101, it presents an excellent value for a comfortable ride.
Train Durham, NC, US to Chicago: Trip Overview
Please note, this information is subject to change.
Train Companies
Based on 5562 reviews, the company was rated 4.1 stars on Busbud. Travellers were especially satisfied with the seats and the ticket access but often complained with the Wi-Fi. Amtrak ticket prices on this trip start at US$198
Durham to Chicago Train
With Busbud, comparing and booking tickets for a train from Durham to Chicago is a breeze. Browse through an extensive selection of train fares and train schedules to find the best deals.
We make it our job to connect you with the most dependable companies that offer train services from Durham to Chicago.
From train tickets to high-end trains trip from Durham to Chicago, we offer a wide range of train services to best suit your needs depending on how much your budget is.
Frequently asked questions on the trip Durham, NC, US - Chicago
How much does a cheap train ticket from Durham to Chicago cost?
The average train ticket price from Durham to Chicago is US$299. The best way to find cheap train tickets from Durham to Chicago is to book your tickets as early as possible. Prices tend to rise as your travel date approaches, so book in advance to secure the best prices!
How long is the train trip from Durham to Chicago?
A train trip between Durham and Chicago is around 1d 15h, although the fastest train will take about 1d 15h. This is the time it takes to travel the 999 km that separates the two cities.
How many daily train are there between Durham and Chicago?
The number of trains from Durham to Chicago can differ depending on the day of the week. On average, there is 1. Some trains are direct while others have layovers. Simplify your train trip from Durham to Chicago by comparing and selecting the train that fits your travel style and budget on Busbud.
Which train companies travel from Durham to Chicago?
When taking the train from Durham to Chicago, you can travel comfortably and safely with Amtrak.
Find cheapest prices for trains
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Durham, NC, US to Chicago was searched and found on 04 Nov 2025 with a price of US$202To save money and be sure you have the best seat, it's a good idea to buy your train tickets from Durham, NC, US to Chicago as early as possible.
You can expect to pay from US$202 to US$1 043 for a train ticket from Durham, NC, US to Chicago based on the last 2 days. You can expect to find the cheapest price for the trip at US$202, which is on 2025-11-04.
About Train Travel
Train Travel Tips
Taking the fastest trains allows you to travel at speeds greater than 300 km/h. Taking a trip from Durham to Chicago is not only much quicker but more comfortable too! You can usually travel directly to the city centre and save time while you're at it.
Whether you take a regional or high-speed train to Chicago, you’ll help reduce the environmental impact and carbon footprint of your trip. As you watch the landscapes unfold before your eyes, you can tell yourself that with this choice, you are making sure they remain protected.
The train emits up to 30x less CO2 for a trip between Durham and Chicago compared to the same trip made by plane or car. A truly ecological mode of transport that will allow you to easily reduce your carbon footprint.
Tune out to the fine sounds of your best music playlist on your train trip from Durham to Chicago while indulging in miles on end of beautiful scenic views.
Did you know?
New York holds the record for the most platforms and track numbers in a single station. Grand Central Station in Manhattan is one of the largest rail terminals in the world with more than 44 platforms and 67 tracks to accommodate passengers.
One of the deepest train stations in the world is in Kiev. Located at a depth of 105m, it was designed in this way to serve as a shelter in the event of an attack. The second deepest station is in China. Badaling station is located 60m under the Great Wall of China!
Some trains in Sweden can recover more than a fifth of the energy they use by braking. This is especially true with ore trains as they descend from Narvik to Kiruna.
Top Travelled Train Routes
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