Bus from Santa Maria, US to San Francisco, US: Tickets & Timetables

Previously seen journeys

Next departures from Santa Maria to San Francisco on 2 December
Operated byVehicle typeDeparture timeDeparture locationTrip durationArrival timeArrival locationRecommendedPrice and booking link
FlixBusBus
Nicholson Ave
409 Townsend St, SFNo tags
AmtrakBus
Nicholson Ave
Mission St & Fremont StNo tags
FlixBusBus
Nicholson Ave
409 Townsend St, SFNo tags
AmtrakBus
Nicholson Ave
Mission St & Fremont StNo tags
AmtrakBus
Nicholson Ave
Mission St & Fremont StNo tags

Get from Santa Maria to San Francisco

This route is served by bus only

The journey takes about 4 hours 50 minutes, and with fares starting at just R 863, it presents an excellent value for a comfortable ride.

1bus per day
4h 50mAverage duration
361 kmDistance
9kgCO₂ emissions

Frequently asked questions about travelling from Santa Maria, US to San Francisco, US by bus

Please note that timetables, routes, or operator details shown here may be updated or differ at the time of your trip.

  1. How much is the bus ticket from Santa Maria to San Francisco?

    The cheapest bus tickets from Santa Maria to San Francisco start at R 863. The average price for this route is around R 1 232. Busbud recommends booking your tickets in advance for the best chance of getting the lowest possible price.

  2. How long is the bus journey from Santa Maria to San Francisco?

    The average bus journey time from Santa Maria to San Francisco is 4h 50m, covering a distance of 361 km. The fastest bus gets you there in 4h 50m and is operated by FlixBus.

  3. Which bus companies service the Santa Maria to San Francisco route?

    Several major bus companies operate on this route with 1 buses available per day, including services from Amtrak, FlixBus.

  4. What is the earliest and latest departure time for the bus from Santa Maria to San Francisco?

    The earliest bus departs from Santa Maria to San Francisco at 15:15. And the latest bus departs at 15:15.

  5. What are the CO₂ emissions for the bus trip from Santa Maria to San Francisco?

    A bus trip from Santa Maria to San Francisco produces an estimated 9 kg of CO₂, making it a highly eco-friendly travel option and Busbud’s recommended way to travel.

  6. What is the best bus company from Santa Maria to San Francisco?

    According to Busbud customers, the highest-rated bus company on this route is Amtrak, with an average rating of 4.1 out of 5 stars based on 5597 reviews.

  7. Which bus company has the best Wi-Fi from Santa Maria to San Francisco?

    Based on reviews on Busbud, the bus company Amtrak has the best Wi-Fi rating with a score of 3.6.

  8. Which bus company offers the most punctual service from Santa Maria to San Francisco?

    According to Busbud traveller reviews, the most punctual bus company on this route is FlixBus, with a punctuality rating of 3.9 out of 5 stars.

  9. Which bus company has the cleanest buses from Santa Maria to San Francisco?

    According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Amtrak, with a cleanliness rating of 4.5 out of 5 stars.

Find cheapest prices for buses

Price is for a one-way ticket for one passenger and based on past searches.

Best price found
30/11
No data
01/12
No data
Today
R 1 668
03/12
No data
04/12
No data
05/12
No data
06/12
No data
07/12
No data
busbud logoThe cheapest trip from Santa Maria, US to San Francisco, US was searched and found on 02 Dec 2025 with a price of R 1 668

To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Santa Maria, US to San Francisco, US as early as possible.

People from around the world trust Busbud