Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Rodoviária do Tietê | Rodoviária de Santa Cruz do Sul | CheapestFastest |
Last refresh of the prices: Today at 05:48 -03.
Get from São Paulo to Santa Cruz do Sul
The journey takes about 22 hours 25 minutes, and with fares starting at just £54, it presents an excellent value for a comfortable ride.
Where are the popular stops in São Paulo and Santa Cruz do Sul?
Stops in São Paulo
- ATerminal Rodoviário da Barra Funda, Avenida Auro Soares de Moura Andrade, 664 - Barra Funda, São Paulo - SP, 01156-001, Brazil
- CTerminal Intermunicipal do Jabaquara, Rua dos Jequitibás, 80 - Jabaquara, São Paulo - SP, 04321-090
- D
Praça do Patriarca
Praça do Patriarca 78, Centro, São Paulo - SP, Brazil - E
São Paulo
São Paulo - F
Tietê
Terminal Rodoviário do Tietê, Avenida Cruzeiro do Sul, , 1800 Santana , 02030-000 São Paulo, SP
Stops in Santa Cruz do Sul
- A
Rodoviária de Santa Cruz do Sul
Tv. Érico Veríssimo, 400 - Vila Schulz, Santa Cruz do Sul - RS, Brazil
Compare bus companies
Based on 484 reviews, the company was rated 3.7 stars on Busbud. Travellers were especially satisfied with the departure location and the ticket access but often complained with the Wi-Fi. Viação Penha ticket prices on this trip start at £54
Frequently asked questions about travelling by bus from São Paulo to Santa Cruz do Sul
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from São Paulo to Santa Cruz do Sul?
The cheapest coach tickets from São Paulo to Santa Cruz do Sul start from £54. The average price for this route is around £54. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from São Paulo to Santa Cruz do Sul?
The average bus journey time from São Paulo to Santa Cruz do Sul is 22h 25m, covering a distance of 558 miles. The fastest bus can take you there in 22h 25m and is operated by Viação Penha.
Which bus companies service the São Paulo to Santa Cruz do Sul route?
Several major bus companies operate on this route with 1 buses available per day.
What is the earliest and latest departure time for the bus from São Paulo to Santa Cruz do Sul?
The earliest bus departs from São Paulo to Santa Cruz do Sul at 22:45. And the latest bus departs at 22:45.
What are the CO₂ emissions for the bus trip from São Paulo to Santa Cruz do Sul?
A bus journey from São Paulo to Santa Cruz do Sul produces an estimated 22 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from São Paulo to Santa Cruz do Sul was searched and found on 30 Nov 2025 with a price of £51To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from São Paulo to Santa Cruz do Sul as early as possible.
You can expect to pay from £51 to £51 for a bus ticket from São Paulo to Santa Cruz do Sul based on the last 2 days. You can expect to find the cheapest price for the trip at £51, which is on 2025-11-30.
