Next bus departures
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
 | Bus | Holiday Inn Guatemala City | Gasolinera Puma | CheapestFastest | ||||
| Bus | Holiday Inn Guatemala City | Gasolinera Puma | No tags |
Last refresh of the prices: Today at 09:11 CST.
Get from Guatemala City to Santa Ana
The journey takes about 4 hours, and with fares starting at just £28, it presents an excellent value for a comfortable ride.
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Frequently asked questions about travelling by bus from Guatemala City to Santa Ana, SV
Please note that timetables, routes, or operator details shown here may be updated or vary at the time of your journey.
How much is the bus ticket from Guatemala City to Santa Ana?
The cheapest coach tickets from Guatemala City to Santa Ana start from £28. The average price for this route is around £75. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus journey from Guatemala City to Santa Ana?
The average bus journey time from Guatemala City to Santa Ana is 4h, covering a distance of 75 miles. The fastest bus can take you there in 3h 45m and is operated by Transporte del Sol.
Which bus companies service the Guatemala City to Santa Ana route?
Several major bus companies operate on this route with 2 buses available per day, including services from Transporte del Sol, Guatego.
What is the earliest and latest departure time for the bus from Guatemala City to Santa Ana?
The earliest bus departs from Guatemala City to Santa Ana at 06:00. And the latest bus departs at 20:00.
What are the CO₂ emissions for the bus trip from Guatemala City to Santa Ana?
A bus journey from Guatemala City to Santa Ana produces an estimated 3 kg of CO₂, making it a highly eco-friendly choice and a mode of travel recommended by Busbud.
Which is the best bus company from Guatemala City to Santa Ana?
According to Busbud customers, the highest-rated bus company on this route is Transporte del Sol, with an average rating of 3.3 out of 5 stars based on 27 reviews.
Which company has the best Wi-Fi from Guatemala City to Santa Ana?
Based on Busbud reviews, the bus company Guatego has the best Wi-Fi rating with a score of 2.5.
Which bus company offers the most punctual service from Guatemala City to Santa Ana?
According to Busbud traveller reviews, the most punctual bus company on this route is Guatego, with a punctuality rating of 4.0 out of 5 stars.
Which bus company has the cleanest buses from Guatemala City to Santa Ana?
According to Busbud traveller reviews, the bus company with the cleanest buses on this route is Guatego, with a cleanliness rating of 5.0 out of 5 stars.
Find cheapest prices for buses
Price is for a one-way ticket for one passenger and based on past searches.
The cheapest trip from Guatemala City to Santa Ana, SV was searched and found on 30 Nov 2025 with a price of £69To save money and be sure you have the best seat, it's a good idea to buy your bus tickets from Guatemala City to Santa Ana, SV as early as possible.
You can expect to pay from £69 to £69 for a bus ticket from Guatemala City to Santa Ana, SV based on the last 2 days. You can expect to find the cheapest price for the trip at £69, which is on 2025-12-03.
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