Previously seen trips
| Operated by | Vehicle type | Departure time | Departure location | Trip duration | Arrival time | Arrival location | Recommended | Price and booking link |
|---|---|---|---|---|---|---|---|---|
Greyhound + FlixBus | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
Greyhound + FlixBus | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
Greyhound + FlixBus | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
FlixBus + Greyhound | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags | ||||
 | Bus | Panama City Beach Station | Port St. Lucie (Park & Ride) | No tags |
Get from Panama City to Port Saint Lucie
The journey takes about 13 hours 25 minutes, and with fares starting at just $199, it presents an excellent value for a comfortable ride.
Where are the popular stops in Panama City and Port Saint Lucie?
Stops in Panama City
- A
Panama City Greyhound Bus Station
917 Harrison Ave, Panama City, FL 32401
Stops in Port Saint Lucie
- A
Port St Lucie Mobil Gas Bus Stop
1820 Sw Fountainview Blvd, Port Saint Lucie, FL 34986 - B
Port Saint Lucie - Wendys
1790 SW St Lucie W Blvd, Port St Lucie, FL 34986 - C
Port Saint LucieService Plaza
Florida's Turnpike, Milepost 144, Port St Lucie, FL 34984, USA - D
Port Saint Lucie Bus Stop
2198 SW Gatlin Blvd. Port St. Lucie, FL 34953
Compare bus companies
Based on 87407 reviews, the company was rated 3.5 stars on Busbud. Travellers were especially satisfied with the ticket access and the temperature but often complained with the WiFi. Greyhound ticket prices on this trip start at $140
Frequently asked questions about travelling from Panama City, US to Port Saint Lucie by bus
Please note that schedules, routes, or operator details shown here may be updated or vary at the time of your trip.
How much is the bus ticket from Panama City to Port Saint Lucie?
The cheapest bus tickets from Panama City to Port Saint Lucie start from $199. The average price for this route is around $216. Busbud recommends that you book your tickets in advance for a better chance to get the lowest possible price.
How long is the bus ride from Panama City to Port Saint Lucie?
The average bus travel time from Panama City to Port Saint Lucie is 13h 25m, covering a distance of 616 km. The quickest bus can get you there in 1d 1h and is operated by Greyhound.
Which bus companies service the Panama City to Port Saint Lucie route?
Several major bus companies operate on this route with 2 buses available per day.
What are the earliest and latest departure times for the bus from Panama City to Port Saint Lucie?
The earliest bus departs from Panama City to Port Saint Lucie at 7:25am. And the latest bus departs at 12:50pm.
What are the CO₂ emissions for the bus trip from Panama City to Port Saint Lucie?
A bus trip from Panama City to Port Saint Lucie generates an estimated 15 kg of CO₂, making it a highly eco-friendly travel option and a mode of travel recommended by Busbud.
